8.52126

Fmoc-Cys(Trt)-OPfp

Novabiochem^®

• 别名: Fmoc-Cys(Trt)-OPfp, N-α-Fmoc-S-trityl-L-cysteine pentafluorophenyl ester
• 经验公式（希尔记法）: C₄₃H₃₀F₅NO₄S
• CAS号: 115520-21-3
• 分子量: 751.76
• MDL號碼: MFCD00065639
• 分類程式碼代碼: 12352209
• NACRES: NA.22

属性

• 品質等級: 200
• 產品線: Novabiochem^®
• 化驗: ≥97.0% (HPLC)
• 形狀: powder
• 反應適用性: reaction type: Fmoc solid-phase peptide synthesis
• 製造商／商標名: Novabiochem^®
• 應用: peptide synthesis
• 官能基: thiol
• 儲存溫度: 15-25°C
• InChI: 1S/C43H30F5NO4S/c44-35-36(45)38(47)40(39(48)37(35)46)53-41(50)34(49-42(51)52-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-54-43(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,49,51)/t34-/m0/s1
• InChI 密鑰: FDAUCYDVXIPBDR-UMSFTDKQSA-N

说明

一般說明

Pre-formed pentafluorophenyl ester for coupling of cysteine residues for Fmoc SPPS without enantiomerization ^[1,2]. Enables use of bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Cysteine-Containing Peptides

Literature references

^[1] T. Kaiser, et al. (1996) Tetrahedron Lett., 37, 1187.
^[2] Y. X. Han, et al. (1997) J. Org. Chem., 62, 4307

聯結

Replaces: 04-12-1504

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): +14.0 - +17.0 °
Purity (TLC (0004)): <3% DCU
Assay (HPLC, area%): ≥ 97.0% (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315
• 防範說明: P264 - P280 - P302 + P352 - P332 + P313 - P362 + P364
• 危險分類: Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable