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product name
Purmorphamine, InSolution, ≥98%, 50 mM in DMSO, induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells
品質等級
化驗
≥98% (HPLC)
形狀
liquid
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
desiccated (hygroscopic)
protect from light
儲存溫度
−20°C
一般說明
A cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
應用
InSolution Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.
包裝
Packaged under inert gas
警告
Toxicity: Irritant (B)
外觀
A 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
重構
Following initial thaw, aliquot and freeze (-20°C).
其他說明
Wu, X., et al. 2004. Chem. Biol.11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Warning
危險聲明
危險分類
Muta. 2
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
188.6 °F - closed cup
閃點（°C）
87 °C - closed cup
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