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Merck
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文件

345810

Millipore

G 418 硫酸盐，经细胞培养测试，大包装

G418 also known as Geneticin is an aminoglycoside antibiotic related to Gentamicin. Used as a selective agent in transfection of eukaryotic cells. Has highest potency ≥730 µg/mg and purity ≥98%.

别名:

G 418 硫酸盐，经细胞培养测试，大包装, G418，G 418，NMD抑制剂I

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About This Item

经验公式（希尔记法）:
C20H40N4O10 · 2H2SO4
CAS号:
108321-42-2
分子量:
692.71
MDL號碼:
MFCD00058314
分類程式碼代碼:
12352200

品質等級

100

化驗

≥98% (TLC)

形狀

powder

製造商／商標名

Calbiochem®

儲存條件

OK to freeze

雜質

≤1.0% Ammonia

顏色

white

溶解度

water: 100 mg/mL, clear, colorless

正離子痕跡

heavy metals: ≤100 ppm

運輸包裝

ambient

儲存溫度

10-30°C

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

InChI 密鑰

UHEPSJJJMTWUCP-NKCAIAFTSA-N

一般說明

也提供无菌过滤水溶液（货号 345812），在 100 mM HEPES 中的无菌过滤溶液（货号 508940）和无菌过滤溶液 PBS（货号509227）中的25 mM溶液。

警告

毒性：标准处理（A）

重構

重悬后，通过 0.22 µm 或 0.45 µm 孔径的过滤器过滤，等分并冷冻（-20°C）（长期储存），或冷藏（4°C）（短期储存）。无菌储备溶液在 -20°C 下可稳定保存长达 1 年。

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H317,H334

危險分類

Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

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Qin Zhou et al.
Biotechnology journal, 16(9), e2000623-e2000623 (2021-05-31)
Chinese hamster ovary (CHO) cells with a high viable cell density (VCD), resilience to culture stress, and the capacity to continuously express recombinant proteins are highly desirable. Phosphatase and tension homology deleted on chromosome ten (PTEN) functions as a key
Wilfried Weber et al.
Methods in molecular biology (Clifton, N.J.), 267, 451-466 (2004-07-23)
Inducible expression of desired transgenes in mammalian cells and animals is a current priority in basic and applied research, biopharmaceutical manufacturing, gene therapy, and tissue engineering, as well as in drug discovery. Among the most prominent human-compatible transgene control technologies
Jiacheng Lin et al.
PLoS pathogens, 18(1), e1010204-e1010204 (2022-01-15)
The hepatitis B virus (HBV) core protein (HBc) functions in multiple steps of the viral life cycle. Heteroaryldihydropyrimidine compounds (HAPs) such as Bay41-4109 are capsid protein allosteric modulators that accelerate HBc degradation and inhibit the virion secretion of HBV, specifically
Yao Fan et al.
Cell death & disease, 13(4), 404-404 (2022-04-27)
Hepatitis B virus infection remains a major health problem worldwide due to its high risk of liver failure and hepatocellular carcinoma. Covalently closed circular DNA (cccDNA), which is present as an individual minichromosome, serves as the template for transcription of
Transgene control engineering in mammalian cells.
Beat P Kramer et al.
Methods in molecular biology (Clifton, N.J.), 308, 123-143 (2005-08-06)
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