218725

Caspase-5, Human, Recombinant, E. coli

Caspase-5, Human, Recombinant, is expressed in E. coli. It is an inflammatory caspase.

• 别名: ICErel-III, TY
• UNSPSC代码: 12352202
• NACRES: NA.77

属性

• 重组: expressed in E. coli
• 质量水平: 100
• 方案: ≥80% (SDS-PAGE)
• 表单: liquid
• 比活: ≥100,000 units/mg protein
• 制造商/商品名称: Calbiochem^®
• 储存条件: OK to freeze; avoid repeated freeze/thaw cycles
• 运输: wet ice
• 储存温度: −70°C

说明

一般描述

M.W. 10,000 and 22,000 (heterodimer).

Recombinant, human caspase-5 expressed in E. coli. A member of the caspase-1 subfamily of cysteine proteases involved in Fas-mediated apoptosis. Caspase-5 cleavage site is reported to be Asp³¹¹ and Asp³³⁰. May also cleave at Asp¹²¹. Suitable for the study of enzyme regulation and kinetics, target substrate cleavage, and inhibitor screening. MW: 10000 and 22000.

警告

Toxicity: Standard Handling (A)

单位定义

One unit is defined as the amount of enzyme that will cleave 1.0 pmol substrate Ac-LEHD-pNA (Cat. No. 218805) per min at 25°C, pH 7.4.

外形

In 100 mM NaCl, 50 mM HEPES, 10 mM DTT, 1 mM EDTA, 10% glycerol, 0.5% CHAPS, pH 7.4.

重悬

After initial defrost, aliquot and freeze at -70°C.

其他说明

Schwartz, S. et al. 1999. Cancer Res. 59, 2995.
Fucheu, C., et al. 1996. Eur. J. Biochem. 236, 207.
Munday, N.A., et al. 1995. J. Biol. Chem. 270, 15870.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 2