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Merck
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文件

12-140

Sigma-Aldrich

Src Substrate Peptide

Src Substrate Peptide primarily used in Kinase Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.41

品質等級

100

分子量

Mw 1670 Da (1.67 kDa)

製造商／商標名

Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

NM_005417.3
NM_198291.1

UniProt登錄號

P12931

運輸包裝

wet ice

基因資訊

human ... SRC(6714)

一般說明

Synthetic peptide (KVEKIGEGTYGVVYK) corresponding to amino acids 6-20 of p34cdc2.

生化／生理作用

Protein Target: Src
Target Sub-Family: TK

品質

Routinely evaluated in a protein kinase assay as a substrate for Src (p60c-src), (14-117) or Lck (p56lck), active (14-379).

外觀

Lyophilized powder

儲存和穩定性

Stable for 2 years at -20°C

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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B Y Chang et al.
Molecular and cellular biology, 18(6), 3245-3256 (1998-06-20)
To isolate and characterize proteins that interact with the unique domain and SH3 and SH2 domains of Src and potentially regulate Src activity, we used the yeast two-hybrid assay to screen a human lung fibroblast cDNA library. We identified RACK1
Kei Sakamoto et al.
The Journal of biological chemistry, 277(14), 11910-11917 (2002-01-26)
The protein serine/threonine kinase Akt/protein kinase B has been recognized as a critical signaling mediator for multiple cell systems. The function of Akt in skeletal muscle is not well understood, and whether contractile activity stimulates Akt activity has been controversial.
C K Szekeres et al.
The Journal of biological chemistry, 275(49), 38831-38841 (2000-08-23)
12(S)-Hydroxyeicosatetraenoic acid (12(S)-HETE), a 12-lipoxygenase metabolite of arachidonic acid, has multiple effects on tumor and endothelial cells, including stimulation of invasion and angiogenesis. However, the signaling mechanisms controlling these physiological processes are poorly understood. In a human epidermoid carcinoma cell

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