1.06525

碘酸钠

for analysis EMSURE^®

• 别名: 碘酸钠
• 经验公式（希尔记法）: INaO₃
• CAS号: 7681-55-2
• 分子量: 197.89
• MDL號碼: MFCD00003533
• 分類程式碼代碼: 12352302
• 酶委員會索引編號: 231-672-5
• NACRES: NA.21

属性

• 品質等級: 300
• 產品線: EMSURE^®
• 化驗: ≥99.5% (iodometric)
• 形狀: solid
• pH值: 5.8 (25 °C, 90 g/L in H₂O)
• 溶解度: 81 g/L
• 密度: 4.28 g/cm³ at 20 °C
• 體積密度: 1150 kg/m³
• 負離子痕跡: bromide, bromate, chloride, chlorate (as Cl^-): ≤0.02%; iodide (I^-): ≤0.002%; sulfate (SO₄^2-): ≤0.005%
• 正離子痕跡: Cd: ≤0.00005%; Cu: ≤0.0001%; Fe: ≤0.001%; K: ≤0.02%; Mn: ≤0.00005%; N: ≤0.002%; Pb: ≤0.0002%; Zn: ≤0.0001%
• 儲存溫度: 2-30°C
• InChI: 1S/HIO3.Na/c2-1(3)4;/h(H,2,3,4);/q;+1/p-1
• InChI 密鑰: WTCBONOLBHEDIL-UHFFFAOYSA-M

说明

應用

• Comparative Analysis of Molecular Landscape in Mouse Models and Patients Reveals Conserved Inflammation Pathways in Age-Related Macular Degeneration.: This study highlights the use of sodium iodate to induce retinal degeneration in mouse models to explore conserved inflammation pathways relevant to age-related macular degeneration. This model provides insights into potential therapeutic targets for inflammatory diseases of the retina (Liu et al., 2024).


• The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage.: Sodium iodate was utilized to model retinal degeneration, showing the effectiveness of the BET PROTAC inhibitor dBET6 in protecting against retinal damage and modulating inflammatory responses, potentially offering new treatment avenues for retinal diseases (Zhu et al., 2023).


• Sodium Iodate-Induced Degeneration Results in Local Complement Changes and Inflammatory Processes in Murine Retina.: This research delves into the specific inflammatory processes and complement system changes following sodium iodate-induced retinal degeneration in mice, providing a detailed molecular understanding of retinal inflammatory responses (Enzbrenner et al., 2021).


• IL-33trap-mediated IL-33 neutralization does not exacerbate choroidal neovascularization, but fails to protect against retinal degeneration in a dry age-related macular degeneration model.: The study used sodium iodate to induce retinal degeneration and test IL-33 neutralization′s effectiveness in preventing retinal damage, contributing to the understanding of inflammatory pathways in retinal diseases (Van Hove et al., 2021).


• An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy.: Utilizing sodium iodate to create an acute retinal injury model, this study mimics the phenotypic characteristics of geographic atrophy, providing a valuable tool for studying this condition and testing potential treatments (Bhutto et al., 2018).

分析報告

含量测定（碱量滴定） ≥ 99.5 %
pH 值（5 %；水）：5 - 8
氯化物、氯酸盐、溴化物、溴酸盐（以 Cl 计）： ≤ 0.02 %
碘化物（I）： ≤ 0.002 %
硫酸盐（SO₄）： ≤ 0.005 %
总氮（N）： ≤ 0.002 %
Cd（镉）： ≤ 0.00005 %
Cu（铜）： ≤ 0.0001 %
Fe（铁）： ≤ 0.001 %
K（钾）： ≤ 0.02 %
Mn（锰）： ≤ 0.00005 %
Pb（铅）： ≤ 0.0002 %
Zn（锌）： ≤ 0.0001 %

法律資訊

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS03,GHS07,GHS08
• 訊號詞: Danger
• 危險聲明: H272 - H302 - H317 - H334
• 防範說明: P210 - P220 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312
• 危險分類: Acute Tox. 4 Oral - Ox. Sol. 2 - Resp. Sens. 1 - Skin Sens. 1
• 儲存類別代碼: 5.1B - Oxidizing hazardous materials
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable