推荐产品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
2F3.2, monoclonal
物種活性
human
製造商／商標名
Upstate®
技術
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同型
IgG2a
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... ZAP70(7535)
相关类别
一般說明
Note: This product is for research use only. It is not manufacured for diagnostic or therapeutic use in humans or animals.
特異性
human ZAP-70, does not recognize murine ZAP-70
免疫原
GST-fusion to tandem SH2 domains of human ZAP-70 corresponding to residues 1-254
應用
Detect ZAP-70 using this Anti-ZAP-70 Antibody, clone 2F3.2 validated for use in FC, IH, IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
Immunological Signaling
Immunological Signaling
品質
routinely evaluated on RIPA lysates prepared from Jurkat cells or Hut-78 cell lysate
標靶描述
70kDa
外觀
Protein G Chromatography
Format: Purified
PBS
儲存和穩定性
2 years at -20°C
分析報告
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Marta Crespo et al.
The New England journal of medicine, 348(18), 1764-1775 (2003-05-02)
The mutational status of immunoglobulin heavy-chain variable-region (IgVH) genes in the leukemic cells of chronic lymphocytic leukemia (CLL) is an important prognostic factor in the disease. We investigated whether the expression of ZAP-70 by CLL cells correlated with the IgVH
TCR signaling: another Abl-bodied kinase joins the cascade.
Wange, Ronald L
Current Biology, 14, R562-R564 (2004)
D H Chu et al.
Immunological reviews, 165, 167-180 (1998-12-16)
The processes of T-cell development and activation employ similar immature and mature receptors as well as similar signal transduction pathways to achieve different outcomes. Many signaling molecules are shared between the receptor signaling pathways, including two families of cytoplasmic protein
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