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Merck

P-010

Supelco

戊巴比妥标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material

品質等級

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

forensics and toxicology

形式

single component solution

儲存溫度

2-8°C

SMILES 字串

CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

InChI

1S/C11H18N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

InChI 密鑰

WEXRUCMBJFQVBZ-UHFFFAOYSA-N

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一般說明

戊巴比妥是一种短效巴比妥和催眠药,已被批准用于治疗癫痫发作和术前镇静。戊巴比妥钠盐,也称为戊巴比妥,在兽医学中用作麻醉剂。该认证的溶液标准适用于法医分析、临床毒理学或尿液药物测试中的 GC/MS 和 LC/MS 测试应用。

應用

  • 恒河猴口服戊巴比妥摄入:禁食和饱腹条件下药物浓度的影响。: 本研究考察了不同浓度口服戊巴比妥对恒河猴摄食行为的影响,探讨了药物作用与营养状况之间的关系(Kliner DJ et al., 1989)。
  • 对乙醇有高偏好度和低偏好度的大鼠和小鼠致醉酒类的饮用。: 这项研究考察了对乙醇有不同偏好度的啮齿动物的饮酒行为,包括了接触戊巴比妥等物质时的饮酒模式数据,提供了关于遗传倾向和镇静剂反应的见解(York JL, 1981)。

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


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Nassir Mansour et al.
Journal of neurosurgery. Pediatrics, 12(1), 37-43 (2013-05-07)
Barbiturates are widely used in the management of high intracranial pressure (ICP) caused by diffuse brain swelling. The cardiovascular, renal, and immunological side effects of these drugs limit them to last-line therapy. There are few published data regarding the role
M Katayama et al.
Laboratory animals, 47(2), 122-126 (2013-04-09)
Pharmacokinetics of drugs may differ between small and large mammals (including humans); therefore, drug testing in animal models must be carefully designed. Sprague-Dawley rats were used in cardiac experiments, during which the lopinavir concentration in serum had to match human
Brandon H Gilroyed et al.
Journal of veterinary science, 14(1), 103-106 (2013-02-08)
In the event of an infectious disease outbreak in cattle, carcasses must be disposed of in a rapid and contained manner. This brief communication details injection of a barbiturate to euthanize cattle inoculated with Escherichia coli O157:H7 followed by carcass
Sarah A Mellion et al.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 14(3), 239-247 (2013-02-09)
To evaluate high-dose barbiturates as a second-tier therapy for pediatric refractory intracranial hypertension complicating severe traumatic brain injury. This is a retrospective cohort study of children with refractory intracranial hypertension treated with high-dose barbiturates. A single center level I pediatric
Pentobarbital for refractory intracranial hypertension: time to "go retro"?
Paul M Shore
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 14(3), 323-324 (2013-03-07)

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