D-010

1,2-二硝基甘油 溶液

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• 经验公式（希尔记法）: C₃H₆N₂O₇
• CAS号: 621-65-8
• 分子量: 182.09
• EC號碼: 200-835-2
• MDL號碼: MFCD00661060
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329798580
• NACRES: NA.24

属性

• 等級: certified reference material
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 1.0 mg/mL in acetonitrile
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: pharmaceutical (small molecule)
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: OC[C@@H](O[N+]([O-])=O)CO[N+]([O-])=O
• InChI: 1S/C3H6N2O7/c6-1-3(12-5(9)10)2-11-4(7)8/h3,6H,1-2H2
• InChI 密鑰: GFVHBTOOPNJKLV-UHFFFAOYSA-N

说明

一般說明

1，2-二硝基甘油是药物血管扩张剂硝酸甘油的主要血浆代谢产物。该经认证的加标溶液^®适用于药学研究或临床毒理学中基于色谱或质谱的应用。硝酸甘油用于治疗心脏病，例如心绞痛和慢性心力衰竭。

應用

• Pharmacokinetics of transdermal nitroglycerin: Research demonstrates the pharmacokinetic profiling of nitroglycerin and its metabolites from a transdermal delivery system, including 1,2-Dinitroglycerin, which contributes to its sustained release and absorption characteristics. This study supports its use in controlled drug delivery applications (Auclair et al., 1998).



• Nitroglycerin metabolism research: Analytical techniques for studying the metabolism of nitroglycerin, including the role of 1,2-Dinitroglycerin, were detailed, highlighting methods for examining nitrite and glutathione interactions. This research aids in understanding the metabolic pathways and implications of nitroglycerin derivatives in pharmacology (Curry et al., 1987).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS02,GHS07
• 訊號詞: Danger
• 危險聲明: H225,H302 + H312 + H332,H319
• 防範說明: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 35.6 °F - closed cup
• 閃點（°C）: 2 °C - closed cup