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Merck

850311P

Avanti

DOCP

Avanti Research - A Croda Brand 850311P, powder

别名:

2-((2,3-二(油酰氧基)丙基)二甲基胺)磷酸氢乙酯

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About This Item

经验公式(希尔记法):
C43H82NO8P
分子量:
772.09
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 100 mg (850311P-100mg)
pkg of 1 × 200 mg (850311P-200mg)

製造商/商標名

Avanti Research - A Croda Brand 850311P

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(C[N+](C)(CCOP([O-])(O)=O)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

一般說明

反向磷酸胆碱脂质是常见磷脂的再混合物,其头基相对于磷酸胆碱(PC)脂质具有相反的电荷方向。iPC脂质头基具有与双层界面相邻的季胺和延伸到水相中的磷酸盐。因此,iPC脂质提供了一个独特的机会来研究双层表面电荷反转的生物物理和生物活性相关分支。

應用

DOCP适用于制备
  • 用于人C反应蛋白结合研究的支持性磷脂单层
  • 大单层囊泡(LUVs)
  • 用于人星形胶质细胞摄取研究的脂质体

包裝

20 mL透明玻璃螺旋盖小瓶(850311P-200mg)
5 mL棕色玻璃螺旋盖小瓶(850311P-100mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


分析证书(COA)

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Sulfocerebrosides upregulate liposome uptake in human astrocytes without inducing a proinflammatory response
Suesca , et al.
Cytometry. Part A : the Journal of the International Society For Analytical Cytology, 83(7), 627-635 (2013)
Specific binding of human C-reactive protein towards supported monolayers of binary and engineered phospholipids
Goda T and Miyahara Y
Colloids and Surfaces. B, Biointerfaces, 161, 662-669 (2018)
Inorganic cadmium affects the fluidity and size of phospholipid based liposomes
Kerek EM and Prenner EJ
Biochimica et Biophysica Acta - Biomembranes, 1858(12), 3169-3181 (2016)
Yibo Liu et al.
Langmuir : the ACS journal of surfaces and colloids, 34(32), 9337-9348 (2018-03-13)
Phospholipids are a major component of the cell membrane. In most natural phospholipids, the phosphate acts as a bridge, connecting the other portion of the polar headgroup with the hydrophobic tails. Such bridging phosphate is chemically quite inert. Synthetic lipids
Emily K Perttu et al.
Journal of the American Chemical Society, 134(10), 4485-4488 (2012-03-01)
Zwitterionic inverse-phosphocholine (iPC) lipids contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Neutral iPC

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