QBD10260

m-dPEG^®₈-NHS ester

• 别名: 2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid succinimidyl ester, 2,5-Dioxo-1-pyrrolidinyl 4,7,10,13,16,19,22,25-octaoxahexacosanoate, Polyethylene glycol
• 经验公式（希尔记法）: C₂₂H₃₉NO₁₂
• CAS号: 756525-90-3
• 分子量: 509.54
• MDL號碼: MFCD13184969
• 分類程式碼代碼: 12352108
• PubChem物質ID: 329823901
• NACRES: NA.22

属性

• 化驗: >90%
• 形狀: solid or viscous liquid
• 反應適用性: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• 聚合物結構: shape: linear; functionality: monofunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: O=C(CCOCCOCCOCCOCCOCCOCCOCCOC)ON1C(CCC1=O)=O
• InChI: 1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3
• InChI 密鑰: IBZNTYBFTKFSMU-UHFFFAOYSA-N

说明

特點和優勢

The m-dPEG^®₈-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₈-NHS ester reacts with amines.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable