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Merck

P73404

Sigma-Aldrich

吡咯-2-甲醛

98%

别名:

2-甲酰基吡咯

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About This Item

经验公式(希尔记法):
C5H5NO
CAS号:
分子量:
95.10
Beilstein:
105745
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

表单

crystals

沸点

217-219 °C (lit.)

mp

43-46 °C (lit.)

储存温度

2-8°C

SMILES字符串

[H]C(=O)c1ccc[nH]1

InChI

1S/C5H5NO/c7-4-5-2-1-3-6-5/h1-4,6H

InChI key

ZSKGQVFRTSEPJT-UHFFFAOYSA-N

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一般描述

2-吡咯甲醛是一种杂环合成砌块,由2位连接甲酰基的吡咯环组成,用于生产各种生物活性物质。 高度官能化的2-吡咯甲醛已用作中间体制备吡咯低聚物大环。

应用


  • 用于检测铜绿假单胞菌的基于嘧啶的荧光有机纳米粒子探针:这项研究使用吡咯-2-甲醛开发了一种基于嘧啶的荧光纳米粒子探针,用于检测铜绿假单胞菌,增强了微生物学的诊断能力(Kaur G等人,2015年)。


储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

224.6 °F - closed cup

闪点(°C)

107 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Corey A Rice et al.
The Journal of chemical physics, 126(13), 134313-134313 (2007-04-14)
Intermolecular interactions relevant for antiparallel beta-sheet formation between peptide strands are studied by Fourier transform infrared spectroscopy of the low temperature, vacuum-isolated model compound pyrrole-2-carboxaldehyde and its dimer in the N-H and C=O stretching range. Comparison to quantum chemical predictions
Takumi Ishizuka et al.
Chemical communications (Cambridge, England), 48(88), 10835-10837 (2012-10-04)
Toward new biotechnology by genetic alphabet expansion, we developed an efficient site-specific labeling method for large RNA molecules. The combination of unnatural base pair transcription and post-transcriptional modification by click chemistry enables simple RNA labeling with a wide variety of
Michiko Kimoto et al.
Nucleic acids research, 35(16), 5360-5369 (2007-08-19)
Fluorescent labeling of nucleic acids is widely used in basic research and medical applications. We describe the efficient site-specific incorporation of a fluorescent base analog, 2-amino-6-(2-thienyl)purine (s), into RNA by transcription mediated by an unnatural base pair between s and
Tsuneo Mitsui et al.
Journal of the American Chemical Society, 125(18), 5298-5307 (2003-05-02)
An unnatural hydrophobic base, pyrrole-2-carbaldehyde (denoted as Pa), was developed as a specific pairing partner of 9-methylimidazo[(4,5)-b]pyridine (Q). The Q base is known to pair with 2,4-difluorotoluene (F) as an isostere of the A-T pair, and F also pairs with
Yasushi Hikida et al.
Nature protocols, 5(7), 1312-1323 (2010-07-03)
Methods for fluorescent probing at a defined position of RNA provide powerful tools for analyzing the local structural conformation of functional RNA molecules by tracking fluorescence changes. In this article, we describe the site-specific fluorescent probing of RNA by transcription

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