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Merck

P14815

Sigma-Aldrich

4-乙氧基苯胺

98%

别名:

对氨基苯乙醚, 4-乙氧基苯胺

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About This Item

线性分子式:
C2H5OC6H4NH2
CAS号:
分子量:
137.18
Beilstein:
606666
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

折射率

n20/D 1.559 (lit.)

沸点

250 °C (lit.)

mp

2-5 °C (lit.)

密度

1.065 g/mL at 25 °C (lit.)

SMILES字符串

CCOc1ccc(N)cc1

InChI

1S/C8H11NO/c1-2-10-8-5-3-7(9)4-6-8/h3-6H,2,9H2,1H3

InChI key

IMPPGHMHELILKG-UHFFFAOYSA-N

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象形图

Health hazardExclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

闪点(°F)

251.6 °F - closed cup

闪点(°C)

122 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Esko Kankuri et al.
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The present study was aimed to test the possible cyclooxygenase (COX)-1/COX-2 selectivity of the old analgesic drug phenacetin and its metabolite p-phenetidine, which exhibits high renal toxicity. Paracetamol (acetaminophen), the main metabolite of phenacetin with low renal toxicity, and indomethacin
Morena Gabriele et al.
Drug metabolism and disposition: the biological fate of chemicals, 47(9), 961-965 (2019-06-27)
Human arylacetamide deacetylase (AADAC) is a single microsomal serine esterase involved in the hydrolysis of many acetyl-containing drugs. To date, the presence and activity of the AADAC enzyme in human lungs has been scarcely examined. We investigated its gene and
J D Baty et al.
Journal of chromatography, 353, 329-337 (1986-02-26)
Liquid chromatographic methods were developed for the study of the in vitro acetylation of the sulphonamide drug sulphamethazine and a series of aniline derivatives. The sensitivity of the methods have allowed data on the activity of the N-acetyltransferase enzyme(s) in
V Fischer et al.
Chemico-biological interactions, 60(2), 115-127 (1986-11-01)
The oxidation of the phenacetin metabolites p-phenetidine and acetaminophen by peroxidases was investigated. Free radical intermediates from both metabolites were detected using fast-flow ESR spectroscopy. Oxidation of acetaminophen with either lactoperoxidase and hydrogen peroxide or horseradish peroxidase and hydrogen peroxide
R Larsson et al.
The Journal of pharmacology and experimental therapeutics, 235(2), 475-480 (1985-11-01)
The metabolism of p-phenetidine in microsomes from rabbit kidney and the metabolism of acetaminophen and p-phenetidine in human kidney microsomes to protein binding metabolites were examined. Microsomal preparations from rabbit kidney medulla catalyzed the irreversible arachidonic acid-dependent binding of p-[14C]phenetidine

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