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反應適用性
core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings
相关类别
應用
Step-by-Step Guide for KitAlysis™ High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit
Downloadable experimental excel sheet
Each kit contains 2 customizable screening sets that include the following components:
- 24 (6 x 4) pre-weighed ligands in glass vials loaded with stir bars, topped with cap mat
- Potassium phosphate: 4 pre-weighed vials with product labels and lids
- CuI (soluble source) in preweighed vial
- 4 degassed anhydrous solvents (dioxane, DMAc, toluene, and DMSO) in ampules
- 1 internal standard
- 2 KitAlysis 24-Well reaction block replacement films
- 8 stir bars for stock solutions
- Ampule cracker
Monitor reaction progress via TLC-MS by following this protocol
Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).
特點和優勢
- Designed and tested by synthetic chemists.
- Easily run 24-microscale reaction in parallel.
- Suggested conditions: 10 μmol reactions with 1 μmol catalyst (10 mol%) 0.1 M concentration, and 3 equiv. base.
- Customizable and downloadable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.
法律資訊
推薦
訊號詞
Danger
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3
標靶器官
Central nervous system, Respiratory system
安全危害
儲存類別代碼
3 - Flammable liquids
閃點(°F)
39.2 °F
閃點(°C)
4 °C
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商品
KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.
实验方案
KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.
相关内容
在有机合成中化学反应设计和优化旨在准确改变反应参数以揭示目标分子的最佳路径。
Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.
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