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Merck

KITALYSIS-CUCN

Sigma-Aldrich

KitAlysis High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit-Pack of 2

别名:

Copper Catalyzed C-N Coupling Kit

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About This Item

分類程式碼代碼:
12161503
NACRES:
NA.22

反應適用性

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

相关类别

應用

Screening kit for Copper C-N Cross-Coupling Reactions. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.

Step-by-Step Guide for KitAlysis High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit

Downloadable experimental excel sheet

Each kit contains 2 customizable screening sets that include the following components:
  • 24 (6 x 4) pre-weighed ligands in glass vials loaded with stir bars, topped with cap mat
  • Potassium phosphate: 4 pre-weighed vials with product labels and lids
  • CuI (soluble source) in preweighed vial
  • 4 degassed anhydrous solvents (dioxane, DMAc, toluene, and DMSO) in ampules
  • 1 internal standard
  • 2 KitAlysis 24-Well reaction block replacement films
  • 8 stir bars for stock solutions
  • Ampule cracker

Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

特點和優勢

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reaction in parallel.
  • Suggested conditions: 10 μmol reactions with 1 μmol catalyst (10 mol%) 0.1 M concentration, and 3 equiv. base.
  • Customizable and downloadable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

法律資訊

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

標靶器官

Central nervous system, Respiratory system

安全危害

儲存類別代碼

3 - Flammable liquids

閃點(°F)

39.2 °F

閃點(°C)

4 °C


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商品

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

实验方案

KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.

相关内容

在有机合成中化学反应设计和优化旨在准确改变反应参数以揭示目标分子的最佳路径。

Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.

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