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Merck

A10604

Sigma-Aldrich

2,5-己二酮

97%

别名:

双丙酮

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About This Item

线性分子式:
CH3COCH2CH2COCH3
CAS号:
分子量:
114.14
Beilstein:
506525
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:

蒸汽压

0.43 mmHg ( 20 °C)

方案

97%

折射率

n20/D 1.425 (lit.)

沸点

191 °C (lit.)

mp

−6-−5 °C (lit.)

密度

0.973 g/mL at 25 °C (lit.)

SMILES字符串

CC(=O)CCC(C)=O

InChI

1S/C6H10O2/c1-5(7)3-4-6(2)8/h3-4H2,1-2H3

InChI key

OJVAMHKKJGICOG-UHFFFAOYSA-N

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说明
价格

象形图

Health hazardExclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2

靶器官

Nervous system

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

174.2 °F - closed cup

闪点(°C)

79 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Antônio Felipe F Oliveira et al.
Journal of analytical toxicology, 33(4), 223-228 (2009-05-28)
2,5-Hexanedione (2,5-HD) is the most important metabolite of n-hexane and methyl ethyl ketone in human urine. Urinary 2,5-HD is used as a biomarker for biological monitoring of workers exposed to n-hexane. A simple method using headspace solid-phase microextraction (HS-SPME) and
Hideki Yamasaki et al.
Toxicological sciences : an official journal of the Society of Toxicology, 117(2), 449-456 (2010-07-10)
In the testis, developing germ cells are dependent on supportive physical and paracrine interactions with Sertoli cells. The intimate nature of this relationship is demonstrated by the fact that a toxic insult compromising the stability of Sertoli cells will have
Yan Sun et al.
Archives of toxicology, 86(2), 205-215 (2011-09-09)
Studies have shown that 2,5-hexanedione (2,5-HD) is the main active metabolite of n-hexane in the human body. The toxicity of n-hexane and 2,5-hexanedione has been extensively researched, but toxicity to the reproductive system, especially the impact on female reproductive function
Min-Sun Kim et al.
Toxicology, 260(1-3), 97-103 (2009-05-26)
2,5-Hexanedione (HD), a metabolite of n-hexane, causes central and peripheral neuropathy leading to motor neuron deficits. Although chronic exposure to n-hexane is known to cause gradual sensorimotor neuropathy, there are no reports on the effects of low doses of HD
Sarah N Campion et al.
Toxicological sciences : an official journal of the Society of Toxicology, 117(2), 457-465 (2010-07-10)
Sertoli cells are essential for testicular germ cell maintenance and survival. We made the unexpected observation that x-radiation (x-ray)-induced germ cell loss is attenuated by co-exposure with the Sertoli cell toxicant 2,5-hexanedione (HD). The mechanisms underlying this attenuation of germ

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