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Merck
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文件

911445

Sigma-Aldrich

Polyester bis-MPA dendron, 4 Rhodamine, 1 carboxyl (core)

generation 2

别名:

Bis-MPA dendron, Fluoresenct linker, Fluoresent dendron

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About This Item

经验公式（希尔记法）:
C127H142Cl4N8O18
分子量:
2210.34
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

solid

分子量

generation 2

號表面基團

4

顏色

red to pink

官能基

carboxylic acid (core)

儲存溫度

−20°C

相关类别

一般說明

  • Polymer architecture: Dendron
  • End Group Functionality: Rhodamine
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid

應用

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allow their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers is biocompatible and biodegradable, making them suitable for biomedical applications.
The core of this product is functionalized by carboxyl groups, which can be readily used in bioconjugation. The rhodamine labeled corona allows for application in bioimaging.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Patrik Stenström et al.
Molecules (Basel, Switzerland), 23(8) (2018-08-17)
Herein, we present the first evaluation of cationic dendrimers based on 2,2-bis(methylol)propionic acid (bis-MPA) as nonviral vectors for transfection of short interfering RNA (siRNA) in cell cultures. The study encompassed dendrimers of generation one to four (G1⁻G4), modified to bear
Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

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