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Merck
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文件

860794

Sigma-Aldrich

Z-L-苯丙氨酸氯甲酮

98%

别名:

N-苄氧羰基-L-苯丙氨酰甲基氯酮, ZPCK

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About This Item

线性分子式:
C6H5CH2CH(NHCO2CH2C6H5)COCH2Cl
CAS号:
26049-94-5
分子量:
331.79
EC號碼:
247-432-8
MDL號碼:
MFCD00037114
分類程式碼代碼:
12352204
PubChem物質ID:
24888520
NACRES:
NA.22

化驗

98%

形狀

powder

光學活性

[α]23/D +30°, c = 1 in chloroform

反應適用性

reaction type: solution phase peptide synthesis

mp

107-108 °C (lit.)

應用

peptide synthesis

儲存溫度

−20°C

SMILES 字串

ClCC(=O)[C@H](Cc1ccccc1)NC(=O)OCc2ccccc2

InChI

1S/C18H18ClNO3/c19-12-17(21)16(11-14-7-3-1-4-8-14)20-18(22)23-13-15-9-5-2-6-10-15/h1-10,16H,11-13H2,(H,20,22)/t16-/m0/s1

InChI 密鑰

OYHLRJGDELITAF-INIZCTEOSA-N

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相关类别

應用

酶抑制剂。

象形圖

Corrosion
GHS05

訊號詞

Danger

危險聲明

H314

危險分類

Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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G Jung et al.
Protein science : a publication of the Protein Society, 4(11), 2433-2435 (1995-11-01)
The essential histidine residue of carboxypeptidase Y (CPY) was modified by a site-specific reagent, a chloromethylketone derivative of benzyloxycarbonyl-L-phenylalanine. The single modified histidine residue was converted to N tau-carboxy-methyl histidine (cmHis) upon performic acid oxidation. A peptide containing cmHis was
Inhibition of carboxypeptidase Y by chloromethyl ketone derivatives of benzyloxycarbonyl-L-phenylalanine.
R Hayashi et al.
Journal of biochemistry, 76(6), 1355-1357 (1974-12-01)
L A Johnson et al.
Biochimica et biophysica acta, 953(3), 269-279 (1988-04-14)
The reaction of chymase, a chymotryptic proteinase from human skin, and bovine pancreatic chymotrypsin with a number of time-dependent inhibitors has been studied. An integrated equation, relating product formation with time, has been derived for the reaction of enzymes with
Biogenesis of vaccina: interrelationship between post-translational cleavage, virus assembly, and maturation.
M Silver et al.
Virology, 117(2), 341-356 (1982-03-01)
T Wileman et al.
Cell regulation, 2(9), 753-765 (1991-09-01)
The endoplasmic reticulum, or an organelle closely associated with it, contains proteases that can be used to remove partially assembled or improperly folded proteins. Very little is known at present about the types of protease that degrade these proteins. The
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