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Merck

852228

Sigma-Aldrich

2′-脱氧鸟苷5′-单磷酸 二钠盐 水合物

≥98%

别名:

5′-dGMP 二钠盐

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About This Item

经验公式(希尔记法):
C10H12N5Na2O7P · xH2O
CAS号:
分子量:
391.18 (anhydrous basis)
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥98%

形狀

solid

雜質

≤4% ethanol

mp

>245 °C (dec.) (lit.)

SMILES 字串

[Na+].[Na+].[H]O[H].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP([O-])([O-])=O)O3)C(=O)N1

InChI

1S/C10H14N5O7P.2Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;;1H2/q;2*+1;/p-2/t4-,5+,6+;;;/m0.../s1

InChI 密鑰

HQSJCEYJAGVPJG-BIHLCPNHSA-L

應用

作为反应物,参与以下反应:
  • 溶液中自组装和G-四链体成核/生长分析
  • 亲核捕集
  • 还原性烷化

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Mingfeng Li et al.
PloS one, 8(1), e54420-e54420 (2013-02-01)
Free extracellular DNA provides nutrition to bacteria and promotes bacterial evolution by inducing excessive mutagenesis of the genome. To understand the influence of extracellular DNA fragments on D. radiodurans, we investigated cell growth and survival after extracellular DNA or dNMPs
Yancheng Liu et al.
Photochemistry and photobiology, 88(3), 639-644 (2012-02-11)
Laser flash photolysis studies have been carried out to investigate the reactions of ciprofloxacin (CPX) with 2'-deoxyguanosine-5'-monophosphate (dGMP), N, N, N', N'-tetramethyl-p-phenylenediamine (TMPD) and ferulic acid (FCA) in neutral aqueous solutions, respectively. CPX triplet state ((3)CPX*) can be quenched by
Mariko Higuchi et al.
Journal of structural biology, 173(1), 20-28 (2010-10-05)
MutT distinguishes substrate 8-oxo-dGTP from dGTP and also 8-oxo-dGMP from dGMP despite small differences of chemical structures between them. In this paper we show by the method of molecular dynamics simulation that the transition between conformational substates of MutT is
Jean L Whittingham et al.
The Biochemical journal, 428(3), 499-509 (2010-04-01)
Plasmodium falciparum is the causative agent of malaria, a disease where new drug targets are required due to increasing resistance to current anti-malarials. TMPK (thymidylate kinase) is a good candidate as it is essential for the synthesis of dTTP, a
Mariana P Serrano et al.
Physical chemistry chemical physics : PCCP, 14(33), 11657-11665 (2012-07-25)
UV-A radiation (320-400 nm) induces damage to the DNA molecule and its components through photosensitized reactions. Biopterin (Bip) and its photoproducts 6-formylpterin (Fop) and 6-carboxypterin (Cap) accumulate in the skin of human beings suffering from vitiligo, a depigmentation disorder where

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