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Merck
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文件

803332

Sigma-Aldrich

磺基-SANPAH(磺基琥珀酰亚胺基6（4′-叠氮基-2′-硝基苯氨基）己酸酯

别名:

(sulfosuccinimidyl 6-(4′-azido-2′-nitrophenylamino)hexanoate), 1-[[6-[(4-azido-2-nitrophenyl)amino]-1-oxohexyl]oxy]-2,5-dioxo-3-pyrrolidinesulfonic acid monosodium salt, Sulfo-SANPAH

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About This Item

经验公式（希尔记法）:
C16H17O9N6NaS
分子量:
492.40
分類程式碼代碼:
12352102
PubChem物質ID:
329768797
NACRES:
NA.22

形狀

powder

品質等級

100

分子量

492.4

反應適用性

reagent type: cross-linking reagent

儲存條件

desiccated

溶解度

water: soluble

官能基

azide

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

O=C1CC(S(=O)([O-])=O)C(N1OC(CCCCCNC2=CC=C(N=[N+]=[N-])C=C2[N+]([O-])=O)=O)=O.[Na+]

InChI

1S/C16H18N6O9S.Na/c17-20-19-10-5-6-11(12(8-10)22(26)27)18-7-3-1-2-4-15(24)31-21-14(23)9-13(16(21)25)32(28,29)30;/h5-6,8,13,18H,1-4,7,9H2,(H,28,29,30);/q;+1/p-1

InChI 密鑰

XXUXLXCHYVHAOD-UHFFFAOYSA-M

相关类别

一般說明

ANB-NOS和磺基-SANBAH是异双官能交联剂，含有胺反应性的N-羟基琥珀酰亚胺酯和光活化的硝基苯叠氮化物。NHS酯在pH 7-9缓冲液中与伯氨基（-NH2）有效反应，形成稳定的酰胺键。当暴露在紫外光下时，硝基苯叠氮化合物形成氮烯基团，该基团可以引发双键的加成反应，插入碳氢和氮氢位点，或随后与亲核体（例如伯胺）发生扩环反应。

應用


  • Dynamic Control of Cell Adhesion on a Stiffness-Tunable Substrate for Analyzing the Mechanobiology of Collective Cell Migration: This study uses Sulfo-SANPAH for photochemical cross-linking in cell adhesion research (Kamimura et al., 2017).

  • Evaluation of L929 fibroblast attachment and proliferation on ArgGlyAspSer (RGDS) immobilized chitosan: This paper investigates the use of Sulfo-SANPAH to enhance fibroblast attachment on chitosan substrates (Karakecili et al., 2016).

特點和優勢

  • 反应基团：磺基氨基磺酸酯和硝基苯叠氮化物
  • 对氨基和任何亲核物质有反应
  • 不可切割
  • n-磺基琥珀酰亚胺基-6-（4′-叠氮基-2′-硝基苯氨基）己酸酯
  • 最佳光解发生在320-350纳米；将辐射对生物分子的损害降至最低
  • 水溶性；不可切割

注意

这种产品对湿气很敏感。小瓶包装在带有干燥剂的可再密封袋中，以减少湿气接触。冷藏后，打开前将小瓶平衡至室温，以减少小瓶内的冷凝。制备新的溶液。不建议储存原液。使用后，将小瓶放回可重新密封的袋子中。封闭袋子，在推荐的温度下储存产品。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H319

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

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