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Merck

790877

Sigma-Aldrich

三(2,2,2-三氟乙基)硼酸酯

97%

别名:

三(2,2,2-三氟乙基)硼酸酯, Sheppard 酰胺化试剂, 三(2,2,2-三氟乙氧基)硼, Sheppard 试剂

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About This Item

经验公式(希尔记法):
C6H6BF9O3
CAS号:
分子量:
307.91
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

97%

形狀

liquid

折射率

n/D 1.298 (lit.)

密度

1.430 g/mL at 25 °C

SMILES 字串

FC(F)(F)COB(OCC(F)(F)F)OCC(F)(F)F

InChI

1S/C6H6BF9O3/c8-4(9,10)1-17-7(18-2-5(11,12)13)19-3-6(14,15)16/h1-3H2

InChI 密鑰

DIEXQJFSUBBIRP-UHFFFAOYSA-N

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應用

试剂可促进羧酸和胺在热和微波条件下直接生成酰胺。

象形圖

Flame

訊號詞

Warning

危險聲明

危險分類

Flam. Liq. 3

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

109.9 °F

閃點(°C)

43.3 °C


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Pavel Starkov et al.
Organic & biomolecular chemistry, 9(5), 1320-1323 (2011-01-08)
Simple borates serve as effective promoters for amide bond formation with a variety of carboxylic acids and amines. With trimethyl or tris(2,2,2-trifluoroethyl) borate, amides are obtained in good to excellent yield and high purity after a simple work-up procedure. Tris(2,2,2-trifluoroethyl)
Rachel M Lanigan et al.
The Journal of organic chemistry, 78(9), 4512-4523 (2013-04-17)
B(OCH2CF3)3, prepared from readily available B2O3 and 2,2,2-trifluoroethanol, is as an effective reagent for the direct amidation of a variety of carboxylic acids with a broad range of amines. In most cases, the amide products can be purified by a

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