686344

4,4,5,5-四甲基-1,3,2-二氧磷杂环戊烷-2-醇

95%

• 别名: 2-氧代-4,4,5,5-四甲基-1,3,2-二氧磷杂环戊烷, 4,4,5,5-四甲基-1,3,2-二氧磷杂环戊烷2-氧化物, HASPO-1, 膦酸频哪醇酯, 频哪醇膦酸酯
• 经验公式（希尔记法）: C₆H₁₃O₃P
• CAS号: 16352-18-4
• 分子量: 164.14
• MDL號碼: MFCD09836231
• 分類程式碼代碼: 12352005
• PubChem物質ID: 329761040

属性

• 化驗: 95%
• 形狀: powder
• 反應適用性: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• mp: 99-106 °C
• 官能基: phosphine
• SMILES 字串: CC1(C)O[PH](=O)OC1(C)C
• InChI: 1S/C6H13O3P/c1-5(2)6(3,4)9-10(7)8-5/h10H,1-4H3
• InChI 密鑰: QPONEGYFSLRCLJ-UHFFFAOYSA-N

说明

應用

• Preligand in palladium-catalyzed Kumada cross-coupling reactions of aryl tosylates with Grignard reagents
• Catalyst for reversible chain transfer polymerizations

Reactant for:

• Synthesis of oxapalladacycle as catalyst for Markovnikov-type addition
• Preparation of palladium(II) complexes as catalysts for Heck cross-coupling reactions
• Preparation of palladium catalysts for asymmetric hydrogenation of a-keto phosphonates
• Hydrophosphorylation of alkenes, dienes and enynes in the presence of rhodium catalysts

在空气中稳定的前配体，用于钯催化的 Kumada 型交叉偶联反应。

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H312,H319
• 防範說明: P264 - P280 - P302 + P352 + P312 - P305 + P351 + P338 - P337 + P313 - P362 + P364
• 危險分類: Acute Tox. 4 Dermal - Eye Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves