推荐产品
同位素純度
≥99 atom % 13C
化驗
≥99% (CP)
bp
165 °C
mp
11-12 °C
密度
1.281 g/mL at 25 °C
質量偏移
M+1
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
CC(=O)[13C](O)=O
InChI
1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)/i3+1
InChI 密鑰
LCTONWCANYUPML-LBPDFUHNSA-N
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一般說明
Pyruvic-1-13C 是同位素标记的丙酮酸前体。
應用
超极化 13C标记的丙酮酸及其代谢产物乳酸,用于对实体肿瘤实时代谢通量进行成像,评估肿瘤对化疗、放疗和靶向mTOR药物的反应情况。
包裝
该产品可以大包装形式供货,也可按需进行包装。 如需关于价格、供货形式及包装的信息,请联系稳定同位素客户服务。
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Skin Corr. 1C
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類(WGK)
WGK 1
閃點(°F)
179.6 °F - closed cup
閃點(°C)
82 °C - closed cup
其他客户在看
Cancer research, 73(14), 4190-4195 (2013-06-01)
Hyperpolarized (13)C magnetic resonance spectroscopy provides a unique opportunity to detect real-time metabolic fluxes as a means to measure metabolic treatment responses in vivo. Here, we show that pharmacologic inhibition of lactate dehydrogenase-A suppressed the conversion of hyperpolarized (13)C-pyruvate to
NMR in biomedicine, 26(11), 1496-1500 (2013-06-25)
A change in myocardial metabolism is a known effect of several diseases. MRS with hyperpolarized (13)C-labelled pyruvate is a technique capable of detecting changes in myocardial pyruvate metabolism, and has proven to be useful for the evaluation of myocardial ischaemia
Journal of magnetic resonance imaging : JMRI, 33(6), 1284-1290 (2011-05-19)
To demonstrate the feasibility of using DNP hyperpolarized [1-(13)C]-pyruvate to measure early response to temozolomide (TMZ) therapy using an orthotopic human glioblastoma xenograft model. Twenty athymic rats with intracranial implantation of human glioblastoma cells were divided into two groups: one
Magnetic resonance in medicine, 73(6), 2087-2093 (2014-07-22)
Hyperpolarized [1-(13) C]lactate in solution may be a clinically relevant and safe substrate for real time MR investigations of key metabolic pathways. The potential of using hyperpolarized [1-(13) C]lactate for magnetic resonance studies of cardiac metabolism in vivo was explored.
商品
Review the 10 steps of glycolysis in the Embden-Meyerhof-Parnas glycolytic pathway. Easily compare reaction stages and buy the enzymes for your life science research.
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