675156

(R)-VANOL

97%

• 别名: (2R)-(+)-3,3′-二苯基-[2,2′-联二萘]-1,1′-二醇, (R)-3,3′-二苯基-2,2′-二-1-萘酚
• 经验公式（希尔记法）: C₃₂H₂₂O₂
• CAS号: 147702-13-4
• 分子量: 438.52
• MDL號碼: MFCD08459338
• 分類程式碼代碼: 12352005
• PubChem物質ID: 24885264
• NACRES: NA.22

属性

• 化驗: 97%
• 形狀: solid
• 光學活性: [α]20/D +310°, c = 1 in chloroform
• mp: 200-204 °C
• SMILES 字串: Oc1c(c(cc2ccccc12)-c3ccccc3)-c4c(O)c5ccccc5cc4-c6ccccc6
• InChI: 1S/C32H22O2/c33-31-25-17-9-7-15-23(25)19-27(21-11-3-1-4-12-21)29(31)30-28(22-13-5-2-6-14-22)20-24-16-8-10-18-26(24)32(30)34/h1-20,33-34H
• InChI 密鑰: NDTDVKKGYBULHF-UHFFFAOYSA-N

说明

應用

已证实 VANOL 是用于催化型不对称 Diels-Alder 反应、亚胺羟醛反应以及氮杂环丙化反应的绝佳配体。

(R)-VANOL is a vaulted biaryl ligand that may be used in the following processes:

• Transformation of 3-substituted cyclobutanones to enantiopure γ-butyrolactones via asymmetric Baeyer-Villiger Reaction in the presence of an aluminum catalyst.
• Asymmetric aziridination of N-(4-(Methylsulfonyl)benzylidene)diphenylmethanamine to form (2S,3S)-ethyl 1-benzhydryl-3-(4-(methylsulfonyl)phenyl) aziridine-2-carboxylate.
• Conjugate addition of terminal alkynes to 2-arylidene-1,3-diketones with high enantioselectivity in the presence of diethyl zinc.

安全信息

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H315,H318,H335,H413
• 防範說明: P273 - P280 - P302 + P352 - P305 + P351 + P338 + P310
• 危險分類: Aquatic Chronic 4 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves