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Merck
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文件

568562

Sigma-Aldrich

聚(L-丙交酯-co-己内酯-co-乙交酯)

L-lactide 70 %, average Mn ~50,000 by GPC

别名:

ε-Caprolactone-glycolide-L -lactide copolymer, Poly-L -lactide-co-glycolide-co-ε-caprolactone

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About This Item

CAS号:
134490-19-0
MDL號碼:
MFCD04041034
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

solid

饋電比

lactide:caprolactone:glycolide 70:20:10

分子量

average Mn ~50,000 by GPC

成份

L-lactide, 70%

轉變溫度

Tg ~28 °C

儲存溫度

2-8°C

相关类别

應用

Poly(L-lactide-co-caprolactone-co-glycolide) (PLGA-PCL) is a biodegradable block copolymer that may be used as nanoparticle-based drug delivery systems. Electrospun nanofiber blend of PLGA-PCL, phosphorylcholine groups and an antiproliferative (rapamycin)may be used as vascular grafts and prostheses.

特點和優勢

具有生物相容性且可生物降解的聚合物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Preparation of electrospun poly (L-lactide-co-caprolactone-co-glycolide)/phospholipid polymer/rapamycin blended fibers for vascular application.
Kim H I, et al.
Current Applied Physics, 9(4), e249-e251 (2009)
Novel docetaxel-loaded nanoparticles based on poly (lactide-co-caprolactone) and poly (lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies.
Sanna V, et al.
Nanoscale Research Letters, 6(1), 260-260 (2011)

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