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方案
98%
mp
223-225 °C (dec.) (lit.)
SMILES字符串
OC(=O)c1n[nH]cc1[N+]([O-])=O
InChI
1S/C4H3N3O4/c8-4(9)3-2(7(10)11)1-5-6-3/h1H,(H,5,6)(H,8,9)
InChI key
ZMAXXOYJWZZQBK-UHFFFAOYSA-N
一般描述
已经对这种吡唑对血流的影响 及其钯氢化 进行了研究。
应用
4-Nitro-3-pyrazolecarboxylic acid may be used as a starting reagent for the synthesis of library of pyrazole derivatives, potential A3 adenosine receptor (A3AR) antagonists.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Hydrogenation on Granular Palladium-containing Catalysts: II. Hydrogenation of Nitroheterocyclic Compounds
Russ. J. Org. Chem., 38, 269-271 (2002)
Bo Xuan et al.
Acta pharmacologica Sinica, 23(8), 705-712 (2002-07-31)
Effects of C-nitropyrazoles and C-nitroazoles on ocular blood flow and retinal function recovery after ischemia have been studied. The compounds were tested on ocular blood flow of ocular hypertensive (40 mmHg) rabbit eyes with colored microsphere technique. They were also
Jing Wei et al.
Neurochemistry international, 55(7), 637-642 (2009-06-23)
Adenosine is known to act as a neuromodulator by suppressing synaptic transmission in the central and peripheral nervous system. A(3) adenosine receptor (A(3)AR) antagonists were recently considered as potential drugs for the treatment of cardiac ischemia and inflammation diseases. To
SERS investigation on 4-nitro-3-pyrazolecarboxylic acid adsorbed on palladium-doped silver nanoparticles.
Pergolese B, et al.
Vibrational Spectroscopy, 48(1), 107-112 (2008)
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