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化驗
98%
mp
47-54 °C (lit.)
官能基
acyl chloride
chloro
nitro
SMILES 字串
[O-][N+](=O)c1cc(ccc1Cl)C(Cl)=O
InChI
1S/C7H3Cl2NO3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H
InChI 密鑰
IWLGXPWQZDOMSB-UHFFFAOYSA-N
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一般說明
4-Chloro-3-nitrobenzoyl chloride is an acid halide.
應用
4-Chloro-3-nitrobenzoyl chloride may be employed as acylation reagent for the Friedel-Crafts acylation of activated benzenes such as anisole, veratrole and 1,4-dimethoxybenzene. It may be employed for the synthesis of 4-chloro-4-methoxy-3-nitrobenzophenone. It may be employed as acylation reagent for the acylation reaction of the deactivated amines (2- aminopyrimidine, aminopyrazine).
訊號詞
Danger
危險聲明
危險分類
Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Insights into the N,N-diacylation reaction of 2-aminopyrimidines and deactivated anilines: an alternative N-monoacylation reaction.
Theodorou V, et al.
ARKIVOC (Gainesville, FL, United States), 4, 11-23 (2014)
Tzvetomira Tzanova et al.
European journal of medicinal chemistry, 44(6), 2724-2730 (2008-10-28)
Considering that oxidative stress is strongly implicated in the toxicity of chemotherapy, much effort is focused on the research of diverse antioxidants as protective agents. An efficient synthesis of three novel benzophenones containing 1,3-thiazol moiety (6a-c) is described. Their antioxidant
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