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化驗
98%
形狀
powder
mp
93-98 °C (lit.)
SMILES 字串
Cc1cnc(N)s1
InChI
1S/C4H6N2S/c1-3-2-6-4(5)7-3/h2H,1H3,(H2,5,6)
InChI 密鑰
GUABFMPMKJGSBQ-UHFFFAOYSA-N
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一般說明
2-Amino-5-methylthiazole is a heterocyclic building block. It is one of the major alkaline metabolite of tenoxicam (TX) and meloxicam (MX).
應用
2-Amino-5-methylthiazole may be used in the preparation of acrylamide monomer, 5-methyl-2-thiozyl methacrylamide (MTMAAm).
2-Amino-5-methylthiazole may be used in the preparation of mixed-ligand dien-Cu(II) complexes (dien=diethylenetriamine). It may be used in the preparation of a new series of Schiff mono/dibase coordination compounds, having potential anticancer and antibacterial activities.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Chemphyschem : a European journal of chemical physics and physical chemistry, 9(7), 983-988 (2008-04-18)
The binding of 2-amino-5-methylthiazole to the W191G cavity mutant of cytochrome c peroxidase is an ideal test case to investigate the entropic contribution to the binding free energy due to changes in receptor flexibility. The dynamic and thermodynamic role of
Journal of inorganic biochemistry, 99(2), 467-476 (2004-12-29)
Two novel mononuclear Cu(II) coordination compounds of the type [Cu(dptaS)Cl(2)] and [Cu(dptaS)Br(2)] (dptaS=1,3-propanediamine, N(1)-[3-aminopropyl]-N(3)-[2-thienylmethylidene] or Schiff mono-base of dipropylenetriamine with 2-thiophene-carboxaldehyde) were prepared by the hydrolysis of the di-bases, [Cu(dptaSS)Cl(2)] and [Cu(dptaSS)Br(2)] (dptaSS=1,3-propanediamine, N(1)-[2-thienylmethylidene]-N(3)-[[2-thienylmethylidene]aminopropyl] or Schiff di-base of dipropylenetriamine with
Journal of inorganic biochemistry, 98(8), 1271-1283 (2004-07-24)
A new series of coordination compounds of the starting materials [Cu(dienX(2)Y(2))] and their adducts [Cu(dienXXY(2))(2a-5mt)] (where dien=diethylenetriamine, dienXX=Schiff bases of diethylenetriamine with 2-furaldehyde or 2-thiophene-carboxaldehyde, X=O, S, Y=Cl, Br, NO(3) and 2a-5mt=2-amino-5-methylthiazole) were synthesized by stepwise reactions and their structures
Journal of enzyme inhibition and medicinal chemistry, 23(6), 1011-1017 (2008-11-14)
Highly reactive radicals are implicated in many pathological conditions. The quest for radical scavengers or antioxidants, spans the previous decades. A new series of complexes of the type [Cu (dien) (2a-2tzn) Y(2)] and [Cu (dienXXY(2)) (2a-5mt)] and of the type
Ratio derivative spectrophotometric method for the determination of some oxicams in presence of their alkaline degradation products.
Scientia Pharmaceutica, 71(4), 303-320 (2003)
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