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方案
97%
mp
98-100 °C (lit.)
SMILES字符串
CC(=O)c1cccc(c1)C#N
InChI
1S/C9H7NO/c1-7(11)9-4-2-3-8(5-9)6-10/h2-5H,1H3
InChI key
SBCFGFDAZCTSRH-UHFFFAOYSA-N
应用
3-Acetylbenzonitrile has been used in the preparation of:
- 3-(hydroxyacetyl)benzonitrile
- 3-(1-(3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)-4-methylphenylimino)ethyl)benzonitrile
警示用语:
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Synthesis and in vitro biological activity of N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinamine derivatives.
Mohana KN and Mallesha L.
Bulgarian Chemical Communications, 43(3), 395-400 (2011)
C Y Watson et al.
Bioorganic & medicinal chemistry, 6(6), 721-734 (1998-07-29)
Inhibitors of poly(ADP-ribose)polymerase (PARP) inhibit repair of damaged DNA and thus potentiate radiotherapy and chemotherapy of cancer. 3-Substituted benzamides and 5-substituted isoquinolin-1-ones have been synthesised and evaluated for inhibition of PARP. Reduction of 3-(bromoacetyl)benzamide, followed by treatment with base, gave
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