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Merck

220051

Sigma-Aldrich

N-碘代琥珀酰亚胺

95%

别名:

1-iodo-pyrrolidine-2,5-dione, 1-iodoazolidine-2,5-dione, NIS, succiniodimide

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About This Item

经验公式(希尔记法):
C4H4INO2
CAS号:
分子量:
224.98
Beilstein:
113917
EC號碼:
MDL號碼:
分類程式碼代碼:
12352101
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

95%

形狀

powder

mp

202-206 °C (lit.)

官能基

imide

儲存溫度

2-8°C

SMILES 字串

IN1C(=O)CCC1=O

InChI

1S/C4H4INO2/c5-6-3(7)1-2-4(6)8/h1-2H2

InChI 密鑰

LQZMLBORDGWNPD-UHFFFAOYSA-N

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應用

从 1,6-二炔经过高效的两步工艺制备的高取代的碘苯。与 TFA 一起使用,将硫苷化学选择性地水解为 1-羟基糖苷。从烯烃和苯亚磺酸合成乙烯砜。

訊號詞

Warning

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1B

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Canadian Journal of Chemistry, 84, 66-66 (2006)
Abby J Isaacs et al.
The Journal of thoracic and cardiovascular surgery, 149(5), 1262-1269 (2015-03-21)
Substantial controversy surrounds the choice between a mechanical versus bioprosthetic prosthesis for aortic valve replacement (AVR), based on age. This study aims to investigate national trends and in-hospital outcomes of the 2 prosthesis choices. All patients aged >18 years in
Yoshihiko Yamamoto et al.
Journal of the American Chemical Society, 128(25), 8336-8340 (2006-06-22)
Highly substituted iodobenzenes were efficiently and regioselectively synthesized from readily available 1,6-diynes via two-step process consisting of silver-catalyzed Csp-H iodination and subsequent ruthenium-catalyzed [2 + 2 + 2] cycloaddition of resultant iododiynes. Some of the obtained iodobenzenes were subjected to
Taichi Kano et al.
Journal of the American Chemical Society, 130(12), 3728-3729 (2008-03-07)
A direct asymmetric iodination reaction of aldehydes with NIS was found to be catalyzed by the novel axially chiral bifunctional amino alcohol (S)-1d. This method represents the rare example of the catalytic and highly enantioselective synthesis of optically active alpha-iodoaldehydes.
Cong-Ying Zhou et al.
Organic letters, 12(9), 2104-2107 (2010-04-15)
Iodination of arene-containing natural products employing N-iodosuccinimide catalyzed by In(OTf)(3) at ambient temperature is reported as a versatile and mild method for natural product derivatization amenable to small scale. This process facilitates natural product derivatization of arene moieties for SAR

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