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Merck

219096

Sigma-Aldrich

D -天冬氨酸

99%, for peptide synthesis, ReagentPlus®

别名:

(R)-(-)-氨基琥珀酸, (R)-2-氨基琥珀酸

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About This Item

线性分子式:
HO2CCH2CH(NH2)CO2H
CAS号:
分子量:
133.10
Beilstein:
1723529
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22

产品名称

D -天冬氨酸, ReagentPlus®, 99%

质量水平

产品线

ReagentPlus®

方案

99%

表单

powder

旋光性

[α]20/D −24°, c = 2.3 in 6 M HCl

光学纯度

ee: 98% (GLC)

反应适用性

reaction type: solution phase peptide synthesis

mp

>300 °C (lit.)

应用

peptide synthesis

SMILES字符串

N[C@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1

InChI key

CKLJMWTZIZZHCS-UWTATZPHSA-N

基因信息

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应用


  • 代谢组学分析鉴定差异代谢物作为急性心肌梗死的生物标志物:这项研究利用代谢组学来鉴定急性心肌梗死的生物标志物,展示了D-天冬氨酸在氨基酸代谢中的作用及其潜在的诊断应用。(Zhou等人,2024年)。

法律信息

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Antimo D'Aniello
Brain research reviews, 53(2), 215-234 (2006-11-23)
D-Aspartic acid (d-Asp), an endogenous amino acid present in vertebrates and invertebrates, plays an important role in the neuroendocrine system, as well as in the development of the nervous system. During the embryonic stage of birds and the early postnatal
Akifumi Oda et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3337-3343 (2011-08-30)
Molecular dynamics simulations of amyloid β(1-42) containing D-aspartic acid residues were performed using several continuous solvent models to investigate the usefulness of simulation methods for D-amino acid-containing proteins and peptides. Normal molecular dynamics simulations and replica exchange molecular dynamics simulations
Francesco Errico et al.
Amino acids, 43(5), 1861-1871 (2012-08-02)
Free D-aspartate (D-Asp) occurs in substantial amounts in the brain at the embryonic phase and in the first few postnatal days, and strongly decreases in adulthood. Temporal reduction of D-Asp levels depends on the postnatal onset of D-aspartate oxidase (DDO)
Noriko Fujii et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3141-3147 (2011-07-05)
Homochirality is essential for life. L-Amino acids are exclusively used as substrates for the polymerization and formation of peptides and proteins in living systems. However, d-amino acids, which are enantiomers of L-amino acids, were recently detected in various living organisms
Ikuhiko Noji et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3310-3316 (2011-07-12)
Unusual amino acid residues such as L-β-aspartyl (Asp), D-α-Asp, and D-β-Asp have been detected in proteins and peptides such as α-crystallin in the lens and β-amyloid in the brain. These residues increase with age, and hence they are associated with

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