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Merck

180629

Sigma-Aldrich

二苯基二硒醚

98%

别名:

二苯联硒

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About This Item

线性分子式:
C6H5SeSeC6H5
CAS号:
分子量:
312.13
Beilstein:
2047179
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

杂质

<2% diphenyl selenide

mp

59-61 °C (lit.)

SMILES字符串

[Se]([Se]c1ccccc1)c2ccccc2

InChI

1S/C12H10Se2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H

InChI key

YWWZCHLUQSHMCL-UHFFFAOYSA-N

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一般描述

二苯二硒化物是一种有机硒化合物,是苯硒醇的氧化衍生物。它是苯基硒自由基的来源。它能与多种有机亲核试剂、亲电试剂和自由基反应。

应用

二苯二硒化物的用途:在铜铁氧体纳米颗粒催化剂的存在下,通过芳基卤化物与二苯二砷化物的交叉偶联合成硒化二芳基物。

生化/生理作用

二苯基二硒化物在体内抑制脑、肝和肾脏中的δ-氨基乙酰丙酸脱水酶(δ-ALA-D)。

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E N Maciel et al.
Journal of biochemical and molecular toxicology, 14(6), 310-319 (2000-11-18)
In the present study, the inhibitory effect of diphenyl diselenide and diphenyl ditelluride after in vitro, acute (a single dose), or chronic exposure (14 doses) was examined in mice 24 hours after the last administration. In vitro, diphenyl diselenide, and
Glaecir Roseni Mundstock Dias et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 30(2), 83-89 (2012-01-17)
Cognitive deficits have been observed in different animal models of adult-onset hypothyroidism. Thus, this study was delineated to evaluate whether diphenyl diselenide, an organoselenium compound with neuroprotective and antioxidant properties, could afford protection against the detrimental effects of hypothyroidism on
César Augusto Brüning et al.
Progress in neuro-psychopharmacology & biological psychiatry, 38(2), 168-174 (2012-03-31)
Bipolar disorder (BD) is a common and severe mood disorder associated with higher rates of suicide and disability. Ouabain, a Na(+)/K(+)-ATPase inhibitor, induces behavioral changes in rats and has been used as a model of mania. The aim of this
Juliana Trevisan da Rocha et al.
Neurobiology of learning and memory, 99, 17-24 (2012-10-23)
This study investigated the effects of co-administration of diphenyl diselenide [(PhSe)(2)] and 17β-estradiol (E(2)) on spatial reference, recognition, and working memories in ovariectomized (OVX) female mice. Sixty-day-old female adult Swiss mice were submitted to ovariectomy. From the 30th until 32nd
Viviane Glaser et al.
Chemico-biological interactions, 206(1), 18-26 (2013-08-21)
Interest in organoselenide chemistry and biochemistry has increased in the past three decades, mainly due to their chemical and biological activities. Here, we investigated the protective effect of the organic selenium compound diphenyl diselenide (PhSe)2 (5 μmol/kg), in a mouse

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