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化驗
97%
形狀
solid
mp
81-83 °C (lit.)
SMILES 字串
COC(=O)\C=C(\C)N
InChI
1S/C5H9NO2/c1-4(6)3-5(7)8-2/h3H,6H2,1-2H3/b4-3+
InChI 密鑰
XKORCTIIRYKLLG-ONEGZZNKSA-N
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一般說明
3-氨基古酸甲酯与结晶茚三酮发生无废物的固态级联反应 。
應用
3-氨基巴豆酸甲酯(3-氨基-2-丁烯酸甲酯)被用于合成具有潜在钙通道阻断活性的4-芳基-1,4-二氢吡啶。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
213.8 °F - closed cup
閃點(°C)
101 °C - closed cup
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
其他客户在看
Chemistry (Weinheim an der Bergstrasse, Germany), 8(3), 594-600 (2002-02-22)
Crystalline ninhydrin (1) undergoes waste-free solid-state cascade reactions with dimedone, L-proline, three o-phenylenediamines, o-mercaptoaniline, two ureas, three thioureas, and methyl 3-aminocrotonate. The yields are quantitative and give pure crystalline products without workup just by milling stoichiometric mixtures of the crystalline
Die Pharmazie, 61(5), 400-405 (2006-05-27)
Synthesis of a new series of 4-aryl-1,4-dihydropyridines possessing potential calcium channel blocking activity along with good vasodilatory profile is reported. The compounds were synthesized using modified Hantzsch condensation of various aldehydes with methyl 3-aminocrotonate in the presence of a catalytic
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