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Merck

119660

Sigma-Aldrich

磷酸三(2-氯乙基)酯

97%

别名:

磷酸三(2-氯乙基)酯

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About This Item

线性分子式:
(ClCH2CH2O)3P(O)
CAS号:
分子量:
285.49
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

蒸汽壓力

<10 mmHg ( 25 °C)

化驗

97%

折射率

n20/D 1.472 (lit.)

bp

192 °C/10 mmHg (lit.)

溶解度

H2O: soluble 7.82 g/L

密度

1.39 g/mL at 25 °C (lit.)

SMILES 字串

ClCCOP(=O)(OCCCl)OCCCl

InChI

1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2

InChI 密鑰

HQUQLFOMPYWACS-UHFFFAOYSA-N

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一般說明

磷酸三(2-氯乙基)酯在塑料中用作阻燃剂,尤其是在汽车和家具中使用的硬质泡沫以及用于建筑保温的硬质泡沫中

應用

通过固相微萃取装置使用三(2-氯乙基)磷酸酯对空气中的有机磷酸酯进行了动态采样

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

449.6 °F - closed cup

閃點(°C)

232 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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H A Tilson et al.
Toxicology and applied pharmacology, 106(2), 254-269 (1990-11-01)
Adult female, Fischer-344 rats were exposed to 275 mg/kg of tris(2-chloroethyl)phosphate (TRCP) by gavage. TRCP produced consistent signs of convulsive activity within 60-90 min after dosing and extensive loss of CAT hippocampal pyramidal cells when examined 7 days after dosing.
H B Matthews et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 20(4), 477-485 (1993-05-01)
Previous short-term studies of tris(2-chloroethyl)phosphate (TRCP), a flame retardant used in industrial and consumer products, demonstrated that repeated administration of 350 mg TRCP/kg body wt by oral gavage resulted in necrosis of pyramidal neurons in the CA1 region of the
H B Matthews et al.
Toxicology and industrial health, 6(1), 1-15 (1990-01-01)
Tris(2-chloroethyl)phosphate (TRCP), a flame-retardant plasticizer used in plastics, polymeric foams and synthetic fibers, was studied as part of the National Toxicology Program's class study of phosphate flame-retardants. TRCP was administered at 0, 22, 44, 88, 175 and 350 mg/kg to
L T Burka et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(2), 443-447 (1991-03-01)
Tris(2-chloroethyl) phosphate (TRCP), a flame retardant, produces a dose-, sex-, and species-dependent lesion in the hippocampal region of the brain following subchronic oral administration. This lesion is more common and more severe in female F344 rats than in male F344
Thorvald Staaf et al.
Journal of environmental monitoring : JEM, 7(9), 883-887 (2005-08-27)
In this study the occurrence of ten organophosphate triesters in indoor air at 29 different locations was investigated. They were detected at all locations and a total of ten compounds were identified. The predominant compounds were the chlorinated compounds tris(chloroisopropyl)

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