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115312

Sigma-Aldrich

N-ω-甲基色胺

99%

别名:

2-(吲哚-3-基)-N-甲基乙胺, 3-(2-[甲氨基]乙基)吲哚, 3-(2-甲基氨基乙基)吲哚, N-单甲基色胺, N10-甲基色胺, 甲基色胺

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About This Item

经验公式（希尔记法）:
C11H14N2
CAS号:
61-49-4
分子量:
174.24
EC 号:
200-507-9
MDL编号:
MFCD00005657
UNSPSC代码:
12352100
PubChem化学物质编号:
24847209
NACRES:
NA.22

质量水平

200

方案

99%

表单

solid

mp

87-89 °C (lit.)

官能团

amine

SMILES字符串

CNCCc1c[nH]c2ccccc12

InChI

1S/C11H14N2/c1-12-7-6-9-8-13-11-5-3-2-4-10(9)11/h2-5,8,12-13H,6-7H2,1H3

InChI key

NCIKQJBVUNUXLW-UHFFFAOYSA-N

应用

N-ω-甲基色胺已用于制备N-乙酰基-α−甲基色胺。
N-ω-甲基色胺已用于通过钩藤(U. tomentosa)蛋白提取物生物合成dolichantoside。
作为反应物用于制备：
  • Manzamine类似物用于控制神经炎症和脑部感染
  • 血清素4受体(5-HT4)受体激动剂
  • Glypetelotine，一种含硫的吲哚生物碱
  • 周期蛋白依赖性激酶(CDK4)的选择性抑制剂
  • 人速激肽NK-2受体拮抗剂
  • 酪氨酸特异性蛋白激酶pp60c-src SH2结构域的抑制剂

包装

无底玻璃瓶。内含物装在锥底内插管中。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCK9960
BCCG4027
BCCF9586
BCCF0898
1430965V

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T Takahashi et al.
The International journal of applied radiation and isotopes, 36(12), 965-969 (1985-12-01)
Five indolealkylamines (N,N-dimethyltryptamine, N-methyltryptamine, bufotenine, O-methylbufotenine, N,N,N-trimethyltryptamine iodide) were labeled with 11C by use of 11CH3I. The labeled compounds were synthesized with a radiochemical yield of 2-50% (based on trapped 11CH3I) in 20-35 min with radiochemical purities of more than
W J VandenHeuvel et al.
Journal of chromatographic science, 21(3), 119-124 (1983-03-01)
This report focuses on recent applications of capillary column GLC to the analysis of drugs and metabolites, other xenobiotics, natural products, and environmental contaminants in samples of biological origin. The increasing use of selected ion monitoring, combined with stable isotope
R N Cory et al.
The Journal of pharmacology and experimental therapeutics, 236(1), 48-54 (1986-01-01)
The contractile response of the isolated rabbit aorta elicited by 5-hydroxytryptamine (5-HT) and five partial agonists acting on the 5-HT2 receptor were separated into a phasic and a tonic response by altering the [Ca++] in the buffer. A kinetic analysis
R W Walker et al.
Journal of chromatography, 289, 223-229 (1984-04-27)
A capillary column gas-liquid chromatography selected ion monitoring-based method was developed for the measurement of [13C,15N]N-methyltryptamine ( NMT ) in human urine. The method was employed to establish the extent of conversion of [13C,15N]tryptamine to the correspondingly labeled NMT in
Strictosidine-related enzymes involved in the alkaloid biosynthesis of Uncaria tomentosa root cultures grown under oxidative stress.
Vera-Reyes I, Huerta-Heredia AA, Ponce-Noyola T, et al.
Biotechnology Progress, doi:10-doi:10 (2013)
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