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Merck

112801

Sigma-Aldrich

吡哆醇 盐酸盐

98%

别名:

PN HCl, 吡哆醇 盐酸盐, 抗皮炎素 盐酸盐, 维生素 B6 盐酸盐

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About This Item

经验公式(希尔记法):
C8H11NO3 · HCl
CAS号:
分子量:
205.64
Beilstein:
3632435
EC號碼:
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:

化驗

98%

形狀

powder

顏色

white to off-white

mp

214-215 °C (lit.)

SMILES 字串

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChI 密鑰

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

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一般說明

Pyridoxine hydrochloride is a water soluble vitamin. It is available through dietary sources like, meat, fish, nuts, vegetables and fruits.

生化/生理作用

Pyridoxine/vitamin B6 is implicated in cellular metabolism, fatty acid biosynthesis, amino acid biosynthesis and catabolism. It is also implicated in the production of neurotransmitters, chlorophyll and plant hormones. Pyridoxine acts as a cofactor for several biochemical reactions. Pyridoxine deficiency is associated with peripheral neuropathy. Pyridoxine hydrochloride is available in parenteral and oral formulations.

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Chapter 40 - Nutritional Deficiencies and Syndromes Associated with Alcoholism
Textbook of Clinical Neurology, 897-917 (2007)
Critical Care Toxicology: Diagnosis and Management of the Critically Poisoned Patient (2017)
Vitamin B6 and its role in cell metabolism and physiology
Parra M, et al.
Cells, 7(7), 84-84 (2018)
Ilan Matok et al.
Journal of clinical pharmacology, 53(3), 334-338 (2013-02-28)
Although Diclectin (doxylamine/pyridoxine delayed-released combination) is widely used in Canada, its pharmacokinetics (PK) during pregnancy has never been described. The objective of this study was to compare the PK of doxylamine/pyridoxine delayed-released combination in pregnant versus nonpregnant women. The apparent
Sonia Fargue et al.
Biochimica et biophysica acta, 1832(10), 1776-1783 (2013-04-20)
Primary hyperoxaluria type 1 (PH1) is a rare hereditary calcium oxalate kidney stone disease caused by a deficiency of the liver-specific pyridoxal-phosphate-dependent peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT). About one third of patients are responsive to pharmacological doses of pyridoxine (vitamin

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