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Merck

107425

Sigma-Aldrich

烟酰肼

97%

别名:

烟酸酰肼

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About This Item

经验公式(希尔记法):
C6H7N3O
CAS号:
分子量:
137.14
Beilstein:
119299
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

97%

mp

159-161 °C (lit.)

溶解度

H2O: soluble 50 mg/mL

SMILES 字串

NNC(=O)c1cccnc1

InChI

1S/C6H7N3O/c7-9-6(10)5-2-1-3-8-4-5/h1-4H,7H2,(H,9,10)

InChI 密鑰

KFUSANSHCADHNJ-UHFFFAOYSA-N

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一般說明

异烟碱酰肼是一种杂环化合物,可用于合成席夫碱。

應用

烟酰肼用于腙文库形成 。用于研究辣根过氧化物酶对异烟酸酰肼(异烟肼)的氧化作用

生化/生理作用

烟酰肼是过氧化物酶的抑制剂 。形成具有较强生物活性的固体金属配合物

準備報告

烟酰肼溶于水中,浓度为 50 mg/mL,形成澄清、无色溶液。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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H A Shoeb et al.
Antimicrobial agents and chemotherapy, 27(3), 399-403 (1985-03-01)
Oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase at the expense of H2O2 yielded reactive species which were able to reduce nitroblue tetrazolium and bleach p-nitrosodimethylaniline. Nicotinic acid hydrazide oxidation did not cause these effects. At slightly alkaline pH
Synthesis, spectroscopic characterization, and crystal structures of Schiff bases derived from nicotinic hydrazide
Diouf F, et al.
IOSR journal of applied chemistry, 1 serie II (2022)
Thermo-chemical behavior of solid nicotinic hydrazide metal complexes in correlation with their stoichiometry.
Sekkina MM and El-Azm MG.
Thermochimica Acta, 77(1), 211-218 (1984)
V Goral et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(4), 1347-1352 (2001-02-15)
Dynamic combinatorial libraries are mixtures of compounds that exist in a dynamic equilibrium and can be driven to compositional self adaptation via selective binding of a specific assembly of certain components to a molecular target. We present here an extension
Nives Galić et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 107, 263-270 (2013-02-26)
Structural forms of aroylhydrazones derived from nicotinic acid hydrazide have been studied in the solid state by FT-IR spectroscopy and in solution by NMR, UV-Vis and ATR spectroscopy. The studied compounds were N'-benzylidene-3-pyridinecarbohydrazide (1), N'-(2,4-dihydroxyphenylmethylidene)-3-pyridinecarbohydrazide (2), N'-(5-chloro-2-hydroxyphenylmethylidene)-3-pyridinecarbohydrazide (3), and N'-(3,5-dichloro-2-hydroxymethoxyphenylmethylidene)-3-pyridinecarbohydrazide

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