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Merck

NDUFS1

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

别名:
CI-75Kd, CI-75k, PRO1304
物种:
UniProtKB ID:
基因ID:
  • Human(4719) Summary: The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(227197) NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • Rat(301458) NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • Zebrafish(493605) NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • chicken(424102) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • domestic guinea pig(100726311) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • naked mole-rat(101698993) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • cow(288380) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • sheep(101115434) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • Goat(100861376) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • domestic cat(101100747) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • dog(478880) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • Horse(100066330) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

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Antibodies

货号
说明
物种反应性
应用
Anti-Complex I-75kD Antibody, from rabbit, purified by affinity chromatography,
物种反应性
bovine, chimpanzee, human, mouse, rat
应用
immunohistochemistry
western blot
Anti-NDUFS1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-NDUFS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
Anti-NDUFS1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-NDUFS1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, canine, human, mouse, rat
应用
ELISA
western blot

Small Molecule - Inhibitor

货号
说明
物种
二甲双胍 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
1,1-二甲双胍 盐酸盐, 97%,
物种
human
二甲双胍 盐酸盐, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
二甲双胍标准液 CRM 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
二甲双胍 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Ndufs1,
物种
mouse
MISSION® esiRNA, targeting human NDUFS1,
物种
human