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Merck

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

别名:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
物种:
UniProtKB ID:
基因ID:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Agonist

货号
说明
物种
甲氧氯普胺, VETRANAL®, analytical standard,
物种
human
甲氧氯普胺, European Pharmacopoeia (EP) Reference Standard,
物种
human
甲氧氯普胺 盐酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human
SR 57227A, solid,
物种
human
甲氧氯普胺 盐酸盐, solid,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
3-(2-氨乙酸)吲哚 盐酸盐, powder,
物种
human
5-羟色胺肌酸酐硫酸盐 一水合物, powder,
物种
human
昂丹司琼 盐酸盐 二水合物, ≥98% (HPLC), powder,
物种
human
1-(4-氯苯基)哌嗪, ≥98.0% (GC),
物种
rat
昂丹司琼 盐酸盐 二水合物, United States Pharmacopeia (USP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
抗血清素受体3A / HTR3A, from rabbit, purified by affinity chromatography,
物种反应性
human
应用
immunohistochemistry
western blot

Small Molecule - Blocker

货号
说明
物种
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human
泽麦定 二盐酸盐, solid,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物种
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human
氟西汀 盐酸盐, solid,
物种
human
利血平, ,
物种
human
盐酸舍曲林 盐酸盐, ≥98% (HPLC),
物种
human

Small Molecule - Ligand

货号
说明
物种
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Precursor

货号
说明
物种
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Htr3a,
物种
mouse
MISSION® esiRNA, targeting human HTR3A,
物种
human