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Merck

CDKN1C

cyclin-dependent kinase inhibitor 1C (p57, Kip2)

别名:
BWCR, BWS, KIP2, WBS, p57, p57Kip2
物种:
UniProtKB ID:
基因ID:
  • Human(1028) Summary: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
  • Mouse(12577) cyclin-dependent kinase inhibitor 1C (P57)
  • Rat(246060) cyclin-dependent kinase inhibitor 1C
  • sheep(100216434) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • naked mole-rat(101726530) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • cow(510972) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • Zebrafish(399483) cyclin-dependent kinase inhibitor 1C

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Antibodies

货号
说明
物种反应性
应用
Anti-p57 KIP2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
immunofluorescence

western blot
p57Kip2 (Kp10) Mouse Monoclonal Antibody, ,
物种反应性
human
应用
immunohistochemistry
Anti-CDKN1C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-Kip2 Antibody, Upstate®, from rabbit,
物种反应性
bovine, human
应用
immunoprecipitation (IP)
western blot
Anti-CDKN1C/p57 Kip2 Antibody, clone 6T4E6, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
核抑制剂, ≥98% (TLC),
物种
human, mouse, rat
奥罗莫星, ≥98% (HPLC),
物种
human, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Cdkn1c,
物种
mouse