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Merck

ADRA2A

adrenoceptor alpha 2A

别名:
ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
物种:
Human ADRA2A (150), Mouse Adra2a (11551), Rat Adra2a (25083), domestic guinea pig Adra2a (100135475), chicken ADRA2A (428980), sheep ADRA2A (100170317), Domestic Rabbit ADRA2A (100009424), Zebrafish adra2a (266750), dog ADRA2A (486888), domestic cat ADRA2A (664736) ...展开
UniProtKB ID:
P08913, B0LPF6, Q2I8G2, Q2XN99, Q86TH8, Q9BZK1
基因ID:
  • Human(150) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11551) adrenergic receptor, alpha 2a
  • Rat(25083) adrenoceptor alpha 2A
  • domestic guinea pig(100135475) adrenergic receptor, alpha 2a
  • chicken(428980) adrenergic, alpha-2A-, receptor
  • sheep(100170317) adrenoceptor alpha 2A
  • Domestic Rabbit(100009424) adrenoceptor alpha 2A
  • Zebrafish(266750) adrenergic, alpha-2A-, receptor
  • dog(486888) adrenoceptor alpha 2A
  • domestic cat(664736) adrenoceptor alpha 2A
  • sheep(101117291) adrenoceptor alpha 2A
  • naked mole-rat(101723298) adrenoceptor alpha 2A
  • cow(282135) adrenergic, alpha-2A-, receptor

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Small Molecule - Agonist

货号
说明
物种
C7897
可乐定 盐酸盐, solid,
物种
human
1302101
Guanfacine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
物种
human
G1043
Guanfacine hydrochloride, ≥98% (HPLC),
物种
human
G110
胍那苄 乙酸盐, powder,
物种
human
T6950
替扎尼定 盐酸盐, ≥98% (HPLC), powder,
物种
human

Small Molecule - Antagonist

货号
说明
物种
127035
1-萘甲基胺, 97%,
物种
rat
Y3125
育亨宾 盐酸盐, ≥98% (HPLC), powder,
物种
human
T13005
1,2,3,4-四氢异喹啉, 95%,
物种
rat, human
I6138
Idazoxan hydrochloride, ,
物种
human
R9525
RX 821002 hydrochloride, solid, ≥98% (HPLC),
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB4500548
抗-肾上腺素受体 α-2A 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB2500033
Anti-ADRA2A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, rat
应用
ELISA
immunocytochemistry
immunofluorescence
SAB4500549
Anti-ADRA2A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
A271
Anti-α2A Adrenergic Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, pig, rat
应用
immunohistochemistry
western blot

Small Molecule - Blocker

货号
说明
物种
M2525
米赛林 盐酸盐, ,
物种
human
A7127
胍丁胺 硫酸盐, ≥97%, powder,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
U104
UK 14,304, ,
物种
human
B9308
BP897, >98% (HPLC), solid,
物种
human, rat
A7257
(−)-去甲肾上腺素, ≥98%, crystalline,
物种
human, rat
H1512
氟哌啶醇, powder,
物种
human, rat
C6305
氯氮平标准液, ,
物种
human, rat

Proteins

货号
说明
物种
HTS096M
ChemiSCREEN Human α2A Adrenergic Receptor Membrane Preparation, Human alpha2A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
物种
human