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Documentos clave

CC065

Sigma-Aldrich

Human Tenascin

from human glioma cell line (U251), liquid, 0.1 mg/mL, suitable for cell culture

Sinónimos:

TN-C, Tenascin, Hexabrachion, Cytotactin, Neuronectin

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About This Item

Código UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.75

Nombre del producto

Human Tenascin-C Purified Protein,

origen biológico

human

Nivel de calidad

100
300

Ensayo

>97% (SDS-PAGE)

Formulario

liquid

mol peso

280—300 kDa

fabricante / nombre comercial

Chemicon®

concentración

0.1 mg/mL

técnicas

cell culture | mammalian: suitable

entrada

sample type induced pluripotent stem cell(s)
sample type mesenchymal stem cell(s)
sample type neural stem cell(s)
sample type pancreatic stem cell(s)
sample type: human embryonic stem cell(s)
sample type epithelial cells
sample type hematopoietic stem cell(s)

solubilidad

water: soluble

Nº de acceso NCBI

Nº de acceso UniProt

Especificidad de unión

Peptide Source: Fibrinogen

Condiciones de envío

dry ice

temp. de almacenamiento

−70°C

Información sobre el gen

human ... TNC(3371)

Descripción general

Product Source: Human glioma cell line (U251).
Purified Human Tenascin-C Protien. Tenascin is known to: 1) play an active role in development of central nervous system and mesenchymal-derived organs; 2) exist in vasculature of tumors in adults; and 3) function in cell adhesion. By SDS-PAGE analysis, the protein migrates around 280-300kD.

Aplicación

Cell adhesion assays.

Optimal working dilutions must be determined by end user.

Ligadura / enlace

Replaces: CC066

Forma física

Purified protein supplied as a liquid in PBS containing no preservatives.

Almacenamiento y estabilidad

Maintain at -70ºC for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Chimwemwe Mwase et al.
Cells, 11(2) (2022-01-22)
Aberrant remodeling of the asthmatic airway is not well understood but is thought to be attributable in part to mechanical compression of airway epithelial cells. Here, we examine compression-induced expression and secretion of the extracellular matrix protein tenascin C (TNC)
Ting-Yu Huang et al.
BioMed research international, 2015, 712546-712546 (2015-04-04)
Urodele amphibians (Ambystoma mexicanum), unique among vertebrates, can regenerate appendages and other body parts entirely and functionally through a scar-free healing process. The wound epithelium covering the amputated or damaged site forms early and is essential for initiating the subsequent
Reza Mirzaei et al.
Oncoimmunology, 7(10), e1478647-e1478647 (2018-10-06)
The dismal prognosis of glioblastoma is attributed in part to the existence of stem-like brain tumor-initiating cells (BTICs) that are highly radio- and chemo-resistant. New approaches such as therapies that reprogram compromised immune cells against BTICs are needed. Effective immunotherapies
Cecelia C Yates et al.
Cell transplantation, 26(1), 103-113 (2016-07-28)
Mesenchymal stem cells (MSCs) remain of great interest in regenerative medicine because of their ability to home to sites of injury, differentiate into a variety of relevant lineages, and modulate inflammation and angiogenesis through paracrine activity. Many studies have found
Janeen H Trembley et al.
Cancer letters, 315(1), 48-58 (2011-11-05)
CK2, a pleiotropic Ser/Thr kinase, is an important target for cancer therapy. We tested our novel tenfibgen-based nanocapsule for delivery of the inhibitor 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole (DMAT) and an siRNA directed against both CK2α and α' catalytic subunits to prostate cancer cells.

Protocolos

This page covers the ECM coating protocols developed for four types of ECMs on Millicell®-CM inserts, Collagen Type 1, Fibronectin, Laminin, and Matrigel.

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