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117455

Sigma-Aldrich

p-Toluenesulfonyl fluoride

98%

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About This Item

Linear Formula:
CH3C6H4SO2F
CAS Number:
Molecular Weight:
174.19
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

solid

reaction suitability

reaction type: click chemistry

bp

112 °C/16 mmHg (lit.)

mp

41-42 °C (lit.)

SMILES string

Cc1ccc(cc1)S(F)(=O)=O

InChI

1S/C7H7FO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3

InChI key

IZZYABADQVQHLC-UHFFFAOYSA-N

General description

p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease.

Application

p-Toluenesulfonyl fluoride was used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation.
Protease inhibitor.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

222.8 °F - closed cup

Flash Point(C)

106 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R M Rathore et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 142(1), 98-106 (2005-07-29)
Digestive enzymes of Catla catla were studied during ontogenic development. Specific amylase activity was 0.12+/-0.01 mg maltose mg protein(-1) h(-1) in fish 4 days after hatching (DAH) and reached a maximum on (0.41+/-0.12 mg maltose mg protein(-1) h(-1)) 34 DAH.
Tomonori Kaneko et al.
Protein science : a publication of the Protein Society, 14(2), 558-565 (2005-01-06)
Growth-limiting stresses in bacteria induce the general stress response to protect the cells against future stresses. Energy stress caused by starvation conditions in Bacillus subtilis is transmitted to the sigma(B) transcription factor by stress-response regulators. RsbP, a positive regulator, is
Nobuyuki Shibata et al.
FEMS microbiology letters, 256(1), 137-144 (2006-02-21)
Lipophilic Malassezia species may induce catheter-associated sepsis in premature neonates and immunocompromised patients receiving parenteral lipid emulsions. To assess the participation of lipolytic enzymes in the pathogenesis of this yeast, we cloned a gene encoding the enzyme. A lipolytic enzyme
Jinkui Yang et al.
Biotechnology letters, 27(15), 1123-1128 (2005-09-01)
Lecanicillium psalliotae produced an extracellular protease (Ver112) which was purified to apparent homogeneity giving a single band on SDS-PAGE with a molecular mass of 32 kDa. The optimum activity of Ver112 was at pH 10 and 70 degrees C (over
Ahmed Fendri et al.
International journal of biological macromolecules, 50(5), 1238-1244 (2012-04-26)
A lipolytic activity was located in the chicken uropygial glands, from which a carboxylesterase (CUE) was purified. Pure CUE has an apparent molecular mass of 50 kDa. The purified esterase displayed its maximal activity (200 U/mg) on short-chain triacylglycerols (tributyrin)

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