1711268

Venlafaxine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : (+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride, Effexor
• Formule empirique (notation de Hill): C₁₇H₂₇NO₂ · HCl
• Numéro CAS: 99300-78-4
• Poids moléculaire : 313.86
• Numéro MDL: MFCD03658865
• Code UNSPSC : 41116107
• ID de substance PubChem : 329751491
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: venlafaxine
• Fabricant/nom de marque: USP
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: Cl[H].COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2
• InChI: 1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
• Clé InChI: QYRYFNHXARDNFZ-UHFFFAOYSA-N
• Informations sur le gène: human ... SLC6A2(6530) , SLC6A4(6532)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Venlafaxine hydrochloride USP reference standard intended for use in specified quality tests and assays.

Also used to prepare standard, system suitability, and standard stock solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP):

• Venlafaxine Hydrochloride
• Venlafaxine Tablets
• Venlafaxine Hydrochloride Extended-Release Capsules
• Desvenlafaxine

Actions biochimiques/physiologiques

Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS09
• Mentions de danger: H411
• Conseils de prudence: P273 - P391 - P501
• Classification des risques: Aquatic Chronic 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable