BP836

Venlafaxine hydrochloride

British Pharmacopoeia (BP) Reference Standard

• Synonyme(s) : (+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride, Effexor
• Formule empirique (notation de Hill): C₁₇H₂₇NO₂ · HCl
• Numéro CAS: 99300-78-4
• Poids moléculaire : 313.86
• Numéro MDL: MFCD03658865
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: venlafaxine
• Forme: solid
• Durée de conservation: limited shelf life, expiry date on the label
• Fabricant/nom de marque: BP
• Application(s): pharmaceutical; pharmaceutical small molecule
• Format: mixture
• Température de stockage: 2-8°C
• Chaîne SMILES: Cl[H].COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2
• InChI: 1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
• Clé InChI: QYRYFNHXARDNFZ-UHFFFAOYSA-N
• Informations sur le gène: human ... SLC6A2(6530) , SLC6A4(6532)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Venlafaxine impurity standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Venlafaxine Tablets

Venlafaxine Prolonged-release Tablets

Venlafaxine Prolonged-release Capsules

Actions biochimiques/physiologiques

Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.

Conditionnement

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS09
• Mentions de danger: H411
• Conseils de prudence: P273 - P391 - P501
• Classification des risques: Aquatic Chronic 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable