Accéder au contenu
Merck
Toutes les photos(2)

Key Documents

View All Documentation

O8382

Sigma-Aldrich

17-Octadecynoic acid

≥95% (GC)

Synonyme(s) :

17-ODYA, Alkynyl Stearic Acid, Octadec-17-ynoic acid

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(2)

About This Item

Formule empirique (notation de Hill):
C18H32O2
Numéro CAS:
34450-18-5
Poids moléculaire :
280.45
Numéro MDL:
MFCD00077382
Code UNSPSC :
12352106
ID de substance PubChem :
24898058
Nomenclature NACRES :
NA.77

Niveau de qualité

200

Pureté

≥95% (GC)

Forme

powder

Solubilité

chloroform: 10 mg/mL to clear, colorless to faintly yellow

Chaîne SMILES 

C#CCCCCCCCCCCCCCCCC(O)=O

InChI

1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h1H,3-17H2,(H,19,20)

Clé InChI

DZIILFGADWDKMF-UHFFFAOYSA-N

Application

17-Octadecynoic acid has been used in lipid synthesis.

Actions biochimiques/physiologiques

17-Octadecynoic acid (7-ODYA) is an irreversible inhibitor of cytochrome P450 isozymes, that participates in long-chain fatty acid metabolism.
Suicide substrate inhibitor that selectively and irreversibly inhibits cytochrome P450 epoxygenases and ω-hydrolases.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Jacob S Yount et al.
Current protocols in chemical biology, 3(2), 65-79 (2011-05-01)
Protein fatty-acylation is the covalent addition of a lipid chain at specific amino acids. This modification changes the inherent hydrophobicity of a protein, often targeting it to cellular membrane compartments. Acylation may also regulate protein activity, stability, and protein-protein interactions.
H Dong et al.
British journal of pharmacology, 120(4), 695-701 (1997-02-01)
1. The nature and cellular mechanisms that are responsible for endothelium-dependent relaxations resistant to indomethacin and NG-nitro-L-arginine methyl ester (L-NAME) were investigated in phenylephrine (PE) precontracted isolated carotid arteries from the rabbit. 2. In the presence of the cyclo-oxygenase inhibitor
Ossama A Hatoum et al.
American journal of physiology. Heart and circulatory physiology, 288(1), H48-H54 (2004-09-04)
The endothelium plays an important role in maintaining vascular homeostasis by synthesizing and releasing several mediators of vasodilation, which include prostacyclin (PGI(2)), nitric oxide, and endothelium-derived hyperpolarizing factor (EDHF). We have recently defined the role of nitric oxide and PGI(2)
Sphingosine-1-phosphate lyase deficient cells as a tool to study protein lipid interactions
Gerl M J, et al.
Testing, 11(4), e0153009-e0153009 (2016)
M H Wang et al.
The Journal of pharmacology and experimental therapeutics, 284(3), 966-973 (1998-03-13)
We characterized the inhibitory activity of several acetylenic and olefinic compounds on cytochrome P450 (CYP)-derived arachidonic acid omega-hydroxylation and epoxidation using rat renal cortical microsomes and recombinant CYP proteins. Among the acetylenic compounds, 6-(2-propargyloxyphenyl)hexanoic acid (PPOH) and N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamide were found
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique