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Key Documents

N9879

Sigma-Aldrich

NADase from porcine brain

≥0.007 unit/mg solid

Synonyme(s) :

DPN Nucleosidase, NAD+ glycohydrolase

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About This Item

Numéro CAS:
Numéro de classification (Commission des enzymes):
Numéro MDL:
Code UNSPSC :
12352204
Nomenclature NACRES :
NA.54

Forme

powder

Niveau de qualité

Activité spécifique

≥0.007 unit/mg solid

Solubilité

insoluble

Température de stockage

−20°C

Description générale

NADase is a glycohydrolase that catalyzes ADP-ribose transfer.

Application

NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling.

Actions biochimiques/physiologiques

Nicotinamide has been shown to inhibit NADase activity.

Définition de l'unité

One unit will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37 °C.

Forme physique

Acetone-dried powder

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Shoko Nakayama et al.
Hematology (Amsterdam, Netherlands), 17(6), 317-320 (2012-11-22)
The accurate determination of cytoplasmic immunoglobulin (cIg) light chain (LC) expression is important to differentiate reactive plasmacytosis from a clonal plasma cell neoplasm such as plasma cell myeloma (PCM). Through retrospective analysis, we studied the cytoplasmic kappa/lambda ratio of CD38-positive
Nicholas Chiorazzi
Hematology. American Society of Hematology. Education Program, 2012, 76-87 (2012-12-13)
Several prognostic markers based on genetic, phenotypic, and molecular characteristics of chronic lymphocytic leukemia (CLL) B cells have emerged in the past decade. The clinical utility of these newer prognostic indicators, alone or in combination with each other and other
Ding-bao Chen et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 41(9), 607-612 (2012-11-20)
To study the clinical and histopathologic features, diagnosis, pathogenesis and therapy of post-transplant lymphoproliferative disorders (PTLD). The clinical and pathologic features of 15 cases of PTLD were retrospectively analyzed by light microscopy, immunohistochemistry and in-situ hybridization, according to the updated
Preparation and Evaluation of Arylazide-Substituted Pyridine Adenine Dinucleotides for Photoaffinity Labeling Experiments
Liu, W., et al.
Photochemistry and Photobiology, 63, 793-799 (1996)
Julien Calvo et al.
PloS one, 7(11), e50495-e50495 (2012-12-05)
Hematopoietic stem cells are responsible for the generation of the entire blood system through life. This characteristic relies on their ability to self renew and on their multi-potentiality. Thus quantification of the number of hematopoietic stem cells in a given

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