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M6876

Sigma-Aldrich

D-Mannose 6-phosphate disodium salt hydrate

≥97.0% dry basis (enzymatic)

Synonyme(s) :

Sodium (2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl phosphate

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About This Item

Formule empirique (notation de Hill):
C6H11Na2O9P · xH2O
Numéro CAS:
33068-18-7
Poids moléculaire :
304.10 (anhydrous basis)
Code UNSPSC :
12352201
ID de substance PubChem :
24897121
Nomenclature NACRES :
NA.25

Source biologique

wood (birch wood)

Niveau de qualité

300

Pureté

≥97.0% dry basis (enzymatic)

Forme

powder

Impuretés

≤1.0% total fructose 6-phosphate and glucose 6-phosphate

Couleur

white to off-white

Solubilité

water: 50 mg/mL, clear, colorless to faintly yellow

Traces de cations

Na: 13.2-17.0% (dry basis)

Température de stockage

−20°C

Chaîne SMILES 

[Na+].[Na+].[H]O[H].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5+,6?;;;/m1.../s1

Clé InChI

UUWJZXLTPORJKW-XTAHGNKUSA-L

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Description générale

Mannose is a monosaccharide.

Application

Mannose has been used in a study to assess the phenotyping of primary human microglia. It has also been used in a study to investigate the identification of Anogeissus latifolia Wallich and analyze refined gum ghatti.

Autres remarques

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Jeroen Melief et al.
Glia, 60(10), 1506-1517 (2012-06-29)
Much is still unknown about mechanisms underlying the phenotypical and functional versatility of human microglia. Therefore, we developed a rapid procedure to isolate pure microglia from postmortem human brain tissue and studied their immediate ex vivo phenotype and responses to
Petra Tiels et al.
Nature biotechnology, 30(12), 1225-1231 (2012-11-20)
Lysosomal storage diseases are treated with human lysosomal enzymes produced in mammalian cells. Such enzyme therapeutics contain relatively low levels of mannose-6-phosphate, which is required to target them to the lysosomes of patient cells. Here we describe a method for
Synthesis of mannose-6-phosphate analogues and their utility as angiogenesis regulators.
Véronique Barragan-Montero et al.
ChemMedChem, 6(10), 1771-1774 (2011-07-28)
Wei Cheong Ngeow et al.
Journal of anatomy, 219(5), 638-645 (2011-08-05)
Microsurgical repair of transected peripheral nerves is compromised by the formation of scar tissue and the development of a neuroma, thereby limiting the success of regeneration. The aim of this study was to quantify histomorphometrically the structural changes in neural
Yunpeng Liu et al.
The Journal of organic chemistry, 76(21), 8682-8689 (2011-10-01)
Mannose-6-phosphate (M6P) containing N-linked glycans are the essential targeting signals for hydrolases sorting in eukaryotic cells. To facilitate their structural and binding analyses, a highly efficient and convergent method has been developed to prepare complex N-linked glycans with well-defined M6P
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