10127647001

D-Glucose 6-phosphate disodium salt hydrate

mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g

• Synonyme(s) : Ester de Robison, G-6-P-Na₂
• Formule empirique (notation de Hill): C₆H₁₁Na₂O₉P · xH₂O
• Numéro CAS: 3671-99-6
• Poids moléculaire : 304.10 (anhydrous basis)
• Numéro Beilstein : 5199009
• Numéro MDL: MFCD00150940
• Code UNSPSC : 12352302
• ID de substance PubChem : 329748950

Propriétés

• Forme: solid
• Poids mol.: (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)
• Conditionnement: pkg of 5 g
• Fabricant/nom de marque: Roche
• Conditions d'expédition: ambient
• Chaîne SMILES: O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O
• InChI: 1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1
• Clé InChI: UUWJZXLTPORJKW-WYFATIGWSA-L

Description

Description générale

Disodium salt

Application

Substrate for glucose-6-phosphatase.

Actions biochimiques/physiologiques

In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.

Composants

77% glucose-6-P (enzymatic), 13% sodium, 8% water

Qualité

Contaminants: <0.2% glucose (enzymatic)

Variante de formule

C₆H₁₁O₉PNa₂

Autres remarques

For life science research only. Not for use in diagnostic procedures.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): does not flash
• Point d'éclair (°C): does not flash