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Key Documents

L8647

Sigma-Aldrich

Levan from Erwinia herbicola

≥98% (TLC)

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About This Item

Numéro CAS:
9013-95-0
Numéro MDL:
MFCD00131502
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

Source biologique

bacterial (Erwinia herbicola)

Niveau de qualité

200

Pureté

≥98% (TLC)

Forme

powder

Technique(s)

thin layer chromatography (TLC): suitable

Couleur

white

Solubilité

water: 9.80-10.20 mg/mL, cloudy to hazy, colorless to faintly yellow

Température de stockage

2-8°C

InChI

1S/C18H32O16/c19-1-7-10(23)14(27)17(5-21,33-7)31-3-9-12(25)15(28)18(6-22,34-9)30-2-8-11(24)13(26)16(29,4-20)32-8/h7-15,19-29H,1-6H2/t7-,8-,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-/m1/s1

Clé InChI

ZFTFOHBYVDOAMH-XNOIKFDKSA-N

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Description générale

Levan is a polysaccharide produced by some microorganisms and plants. It is a non-typical biopolymer composed of fructose units linked by β-(2→6). Levan is an exopolysaccharide (synthesized outside the cell).

Application

Levan from Erwinia herbicola has been used as a:
  • standard for the nuclear magnetic resonance (NMR) spectroscopy analysis of levan produced by Bacillus licheniformis NS032 in sugar beet molasses-based medium
  • polysaccharide substrate to test the ability of Prevotella copri isolates to grow when polysaccharides were provided as the sole carbon source in vitro
  • substrate in levanase activity assay

Actions biochimiques/physiologiques

Levan has various industrial applications like cosmetics, medicine, or nanotechnology. It might exhibit anti-hyperglycemic effect and anti-tumor action, prevent diabetes-induced oxidative stress and increase catalase (CAT) and superoxide dismutase (SOD) in the heart. Levan is also recognized for its immunomodulating and prebiotic actions.

Autres remarques

A polymer of β-D-fructose
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Susanne L Jensen et al.
International journal of biological macromolecules, 85, 514-521 (2016-01-17)
A Levanase, LevB, from Bacillus subtilis 168, was expressed as a His6-tagged protein in Escherichia coli. The enzyme was purified and characterised for its activity and substrate specificity. LevB has a pH optimum of 6.0-6.5 and a maximum observed specific
An evaluation of the prebiotic potential of microbial levans from Erwinia sp. 10119
Liu C, et al.
Journal of functional foods, 64, 103668-103668 (2020)
Hannah Fehlner-Peach et al.
Cell host & microbe, 26(5), 680-690 (2019-11-15)
Gut-dwelling Prevotella copri (P. copri), the most prevalent Prevotella species in the human gut, have been associated with diet and disease. However, our understanding of their diversity and function remains rudimentary because studies have been limited to 16S and metagenomic surveys
G D Gojgic-Cvijovic et al.
International journal of biological macromolecules, 121, 142-151 (2018-10-07)
The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100-140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L
Payal Joglekar et al.
mSphere, 3(3) (2018-05-26)
Genomic differences between gut-resident bacterial strains likely underlie significant interindividual variation in microbiome function. Traditional methods of determining community composition, such as 16S rRNA gene amplicon sequencing, fail to capture this functional diversity. Metagenomic approaches are a significant step forward
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