I6635
Monoclonal Anti-Secretory Component (IgA) antibody produced in mouse
clone GA-1, ascites fluid
Synonyme(s) :
IgA Antibody, Secretory Component Antibody
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About This Item
Produits recommandés
Source biologique
mouse
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
ascites fluid
Type de produit anticorps
primary antibodies
Clone
GA-1, monoclonal
Contient
15 mM sodium azide
Espèces réactives
human
Technique(s)
indirect ELISA: 1:10,000
Isotype
IgG1
Conditions d'expédition
dry ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Description générale
The secretory component is a single chain glycoprotein that may occur freely or as component of the secretory immunoglobulin A (SIgA). IgA regulates the physiological balance between commensal intestinal bacteria and the defenses of the host immune system. It is the highest generated antibody isotype. IgAs are mainly secreted in the intestinal mucosa and prevent the commensal microorganisms from invading the intestines
Monoclonal Anti-Secretory Component (IgA) antibody is specific for secretory human IgA and the free secretory component. The antibody does not bind to human IgG, IgM and IgE.
Monoclonal Anti-Secretory Component (IgA) antibody is specific for secretory human IgA and the free secretory component. The antibody does not bind to human IgG, IgM and IgE.
Immunogène
Secretory component purified from human colostrum
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)
Chromatin immunoprecipitation (1 paper)
Monoclonal Anti-Secretory Component (IgA) antibody has been used in immunohistochemistry analysis and serological assays.
Monoclonal Anti-Secretory Component (IgA) antibody is suitable for use in EIA and western blot. The product may also be used for indirect ELISA (1:10,000).
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Les clients ont également consulté
Alpha Fardah Athiyyah et al.
Iranian journal of microbiology, 11(4), 300-304 (2019-11-14)
Probiotics and prebiotics are known to regulate immune responses. A synbiotic is a product that combines probiotics and prebiotics in a single dosage form. In this study, we attempt to present the effects of a multispecies synbiotic on intestinal mucosa
C G Engeland et al.
Brain, behavior, and immunity, 52, 11-17 (2015-09-01)
Stress-induced impairments of mucosal immunity may increase susceptibility to infectious diseases. The present study investigated the association of perceived stress, depressive symptoms, and loneliness with salivary levels of secretory immunoglobulin A (S-IgA), the subclasses S-IgA1, S-IgA2, and their transporter molecule
Muna Sapkota et al.
Alcoholism, clinical and experimental research, 41(12), 2093-2099 (2017-09-25)
Malondialdehyde (MDA) and acetaldehyde (AA) exist following ethanol metabolism and tobacco pyrolysis. As such, lungs of individuals with alcohol use disorders (AUDs) are a target for the effects of combined alcohol and cigarette smoke metabolites. MDA and AA form a
Min Zhao et al.
Experimental and therapeutic medicine, 14(5), 4033-4040 (2017-10-28)
Redox imbalance is established in various human diseases. Treatment of intestinal epithelial cells with hyperoxia for a prolonged period of time may cause serious effects on redox balance. Secretory component (SC) protein is secreted by intestinal epithelial cells, and has
B Simell et al.
The Journal of infectious diseases, 183(6), 887-896 (2001-03-10)
Local antibodies probably contribute to defense against Streptococcus pneumoniae. This study examined whether pneumococcal carriage and acute otitis media (AOM) induce mucosal antibodies to potential vaccine candidates pneumococcal surface adhesin A (PsaA), pneumolysin (Ply), and pneumococcal surface protein A (PspA).
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